UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	math-22	C46F9.1	6e-78	chrII 1,905,746	C. elegans MATH-22 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	aos-1	C08B6.9	n/a	chrV 10,128,881	aos-1 encodes the C. elegans ortholog of Saccharomyces cerevisiae Aos1p and human SUMO-1 activating enzyme E1 N subunit; by homology, AOS-1 is predicted to form, with a catalytic subunit, UBA-2, a heterodimeric enzyme that activates the ubiquitin-like protein SMO-1/SUMO in preparation for its covalent attachment to target proteins to regulate their subcellular localization and/or stability; in C. elegans, AOS-1 is required for embryonic and larval development, as well as for proper Hox gene regulation; uba-2/aos-1(RNAi) animals that survive embryogenesis show ectopic expression of EGL-5 and ectopic anterior sensory ray formation.
4	H41C03.3	H41C03.3	n/a	chrII 5,848,949	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
5	K07G5.5	K07G5.5	n/a	chrI 7,171,105	contains similarity to Pfam domain PF01545 Cation efflux family contains similarity to Interpro domain IPR002524 (Cation efflux protein)
6	nas-27	T23F4.4	n/a	chrII 1,177,703	nas-27 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-27::GFP promoter fusion is expressed in the reproductive system, the vulva, and the hypodermis.
7	fbxa-54	T12B5.2	n/a	chrIII 957,051	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
8	F19F10.8	F19F10.8	n/a	chrV 7,570,024
9	F54C9.9	F54C9.9	n/a	chrII 8,579,712	contains similarity to Pfam domain PF05178 Krr1 family contains similarity to Interpro domain IPR007851 (Kri1)
10	F49E12.10	F49E12.10	n/a	chrII 8,391,583	contains similarity to Pfam domain PF01598 contains similarity to Interpro domain IPR006088 (Sterol desaturase)
11	srx-29	K06B4.9	n/a	chrV 15,697,466	C. elegans SRX-29 protein ;
12	F59B2.2	F59B2.2	n/a	chrIII 8,995,643	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domains IPR001991 (Sodium:dicarboxylate symporter), IPR013057 (Amino acid transporter, transmembrane)
13	nhr-210	R11G11.12	n/a	chrV 518,366	C. elegans NHR-210 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
14	F39H2.3	F39H2.3	n/a	chrI 8,665,598	contains similarity to Pfam domains PF08669 (Glycine cleavage T-protein C-terminal barrel domain) , PF01571 (Aminomethyltransferase folate-binding domain) contains similarity to Interpro domains IPR006222 (Glycine cleavage T-protein, N-terminal), IPR013977 (Glycine cleavage T-protein, C-terminal barrel)
15	F39B2.3	F39B2.3	n/a	chrI 14,788,812	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR016040 (NAD(P)-binding)
16	F16A11.2	F16A11.2	n/a	chrI 9,391,956	contains similarity to Pfam domain PF01139 Uncharacterized protein family UPF0027 contains similarity to Interpro domain IPR001233 (Protein of unknown function UPF0027)
17	ddb-1	M18.5	n/a	chrIV 12,117,957	M18.5 is orthologous to the human gene DAMAGE-SPECIFIC DNA BINDING PROTEIN 1 (127KD) (DDB1; OMIM:600045), which when mutated leads to disease.
18	ula-1	C26E6.8	n/a	chrIII 4,919,320	The ula-1 gene encodes a component of the enzyme that activates NED-8, which in turn is a ubiquitin-like protein whose conjugating enzyme is UBC-12.
19	C30H6.7	C30H6.7	n/a	chrIV 17,381,384	contains similarity to Pfam domains PF00198 (2-oxoacid dehydrogenases acyltransferase (catalytic domain)) , PF02817 (e3 binding domain) contains similarity to Interpro domains IPR004167 (E3 binding), IPR001078 (Catalytic domain of components of various dehydrogenase complexes)
20	vrs-1	ZC513.4	n/a	chrV 8,033,348	vrs-1 encodes a predicted valyl-tRNA synthetase that affects embryonic viability, growth, and morphology
21	tre-3	W05E10.4	n/a	chrV 11,712,817	tre-3 encodes one of four putative trehalases in C. elegans of unknown function, as RNAi analysis has not produced an obvious phenotype; expressed throughout development.
22	C34B2.5	C34B2.5	n/a	chrI 10,675,986	contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR013026 (Tetratricopeptide region)
23	C45G9.5	C45G9.5	n/a	chrIII 5,049,097
24	cln-3.1	F07B10.1	n/a	chrV 11,264,600	cln-3.1 encodes a predicted transmembrane protein that comprises one of three C. elegans homologs of human CLN3, (OMIM:607042, mutations are associated with Batten disease (also known as juvenile neuronal ceroid lipofuscinosis), a recessively inherited childhood neurodegenerative lysosomal storage disease); as loss of cln-3.1 activity via deletion mutation results in no obvious abnormalities, the precise role of cln-3.1 in C. elegans development and/or behavior is not yet known.
25	tin-13	DY3.1	n/a	chrI 8,759,490	C. elegans TIN-13 protein; contains similarity to Pfam domain PF02953 Tim10/DDP family zinc finger contains similarity to Interpro domain IPR004217 (Zinc finger, Tim10/DDP-type)
26	Y57G11C.4	Y57G11C.4	n/a	chrIV 14,766,103	contains similarity to Pfam domain PF05008 Vesicle transport v-SNARE protein contains similarity to Interpro domains IPR000727 (Target SNARE coiled-coil region), IPR007705 (Vesicle transport v-SNARE)
27	C35A11.4	C35A11.4	n/a	chrV 5,391,300	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
28	drs-2	F10C2.6	n/a	chrV 12,050,440	drs-2 encodes a putative aspartyl-tRNA synthetase.
29	B0024.11	B0024.11	n/a	chrV 10,318,482	contains similarity to Pfam domain PF01142 tRNA pseudouridine synthase D (TruD) contains similarity to Interpro domains IPR001656 (tRNA pseudouridine synthase D), IPR011760 (tRNA pseudouridine synthase D, core), IPR017091 (tRNA pseudouridine synthase D, eukaryotic)
30	C32E8.9	C32E8.9	n/a	chrI 3,796,306	contains similarity to Pfam domain PF00378 Enoyl-CoA hydratase/isomerase family contains similarity to Interpro domain IPR001753 (Crotonase, core)
31	D1081.8	D1081.8	n/a	chrI 8,493,557	contains similarity to Pfam domain PF00249 Myb-like DNA-binding domain contains similarity to Interpro domains IPR001005 (SANT, DNA-binding), IPR012287 (Homeodomain-related), IPR014778 (Myb, DNA-binding), IPR009057 (Homeodomain-like), IPR015495 (Myb transcription factor)
32	T13F2.2	T13F2.2	n/a	chrIV 9,797,072	contains similarity to Pfam domain PF02229 Transcriptional Coactivator p15 (PC4) contains similarity to Interpro domains IPR003173 (Transcriptional coactivator p15), IPR009044 (ssDNA-binding transcriptional regulator)
33	Y47D3B.9	Y47D3B.9	n/a	chrIII 11,467,116	contains similarity to Pfam domain PF02892 BED zinc finger contains similarity to Interpro domain IPR003656 (Zinc finger, BED-type predicted)
34	C44C8.4	C44C8.4	n/a	chrIV 891,926	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
35	F44B9.5	F44B9.5	n/a	chrIII 8,015,142	contains similarity to Pfam domain PF02845 CUE domain contains similarity to Interpro domains IPR003892 (Ubiquitin system component Cue), IPR002123 (Phospholipid/glycerol acyltransferase)
36	C26E6.6	C26E6.6	n/a	chrIII 4,936,354	contains similarity to Pfam domain PF00297 Ribosomal protein L3 contains similarity to Interpro domains IPR009000 (Translation elongation and initiation factors/Ribosomal, beta-barrel), IPR000597 (Ribosomal protein L3)
37	C44C8.1	C44C8.1	n/a	chrIV 904,383	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
38	dnc-2	C28H8.12	n/a	chrIII 5,925,025	dnc-2 encodes a member of the dynamitin family that affects spindle alignment in polarized cells in early embryos, nuclear movement, spindle morphology, chromosome segregation, and pronuclear migration.
39	C35A5.3	C35A5.3	n/a	chrV 10,500,362	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
40	pcp-1	ZK112.1	n/a	chrIII 7,759,923	C. elegans PCP-1 protein; contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domain IPR008758 (Peptidase S28)
41	unc-31	ZK897.1	n/a	chrIV 12,780,334	unc-31 encodes a pleckstrin homology (PH) domain-containing protein that is the C. elegans ortholog of human CADPS/CAPS (calcium-dependent activator protein for secretion OMIM:604667); UNC-31 functions in post-docking calcium-regulated dense-core vesicle fusion that is required for egg laying, locomotion, pharyngeal pumping, and recovery from the dauer larval stage; in addition, UNC-31 functions in the insulin receptor signaling pathway that regulates adult life span where it may control Ca[2+]-regulated secretion of an insulin-like ligand; UNC-31 is not required for synaptic vesicle exocytosis; unc-31::gfp transcriptional reporters are expressed in most, if not all, neurons, vulval muscles, vulval cells, the spermatheca, and secretory cells such as the uterine UV1 cells; UNC-31::GFP translational fusions localize to neuronal cell bodies, axonal projections and to sites of synaptic contact, consistent with other dense-core vesicle proteins.
42	E04F6.6	E04F6.6	n/a	chrII 7,198,430	contains similarity to Interpro domain IPR000183 (Orn/DAP/Arg decarboxylase 2)
43	ZK856.5	ZK856.5	n/a	chrV 10,187,411	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domain IPR004843 (Metallophosphoesterase)
44	C18A11.3	C18A11.3	n/a	chrX 8,063,304
45	sfxn-1.5	T04F8.1	n/a	chrX 11,660,570	C. elegans SFXN-1.5 protein; contains similarity to Pfam domain PF03820 Tricarboxylate carrier contains similarity to Interpro domain IPR004686 (Tricarboxylate/iron carrier)
46	F58G6.3	F58G6.3	n/a	chrIV 9,653,835	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domains IPR007274 (Ctr copper transporter), IPR001463 (Sodium:alanine symporter)
47	Y54G11A.2	Y54G11A.2	n/a	chrII 14,253,902	contains similarity to Pfam domain PF05670 Domain of unknown function (DUF814) contains similarity to Interpro domain IPR008532 (Protein of unknown function DUF814)
48	pcp-2	F23B2.12	n/a	chrIV 9,162,862	C. elegans PCP-2 protein; contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domains IPR008758 (Peptidase S28), IPR000258 (Bacterial ice-nucleation proteins octamer repeat)
49	cpin-1	F38E11.3	n/a	chrIV 9,452,280	cpin-1 is orthologous to a mammalian protein variously identified as guanine aminohydrolase (or guanine deaminase, or guanase), cypin, or p51-nedasin.
50	K08H10.6	K08H10.6	n/a	chrV 9,994,779	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)