UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	lev-8	C35C5.5	0	chrX 11,562,231	lev-8 encodes a novel nicotinic acetylcholine receptor (nAChR) alpha subunit that is a member of the ACR-8 group of nAChR subunits; LEV-8 activity is required for normal rates of pharyngeal pumping and for fully wild-type responses (increased egg laying and body wall muscle contraction) to the nAChR agonist and antihelmintic levamisole; expression of a LEV-8::GFP reporter construct begins at the L1 larval stage and is detected in neurons, body wall and uterine muscle cells, and socket cells of the IL and OL mechanosensory neurons; expression in body wall muscles is strongest in the anterior, consistent with increased levamisole resistance of head, or anterior, muscles seen in lev-8 mutant animals.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	ZK892.6	ZK892.6	n/a	chrII 9,979,541	contains similarity to Vibrio parahaemolyticus Hypothetical protein.; TR:Q87PB2
4	C32B5.5	C32B5.5	n/a	chrII 974,906	contains similarity to Pfam domain PF00646 F-box domain
5	F53F1.1	F53F1.1	n/a	chrV 13,405,004	contains similarity to Pfam domains PF00169 (PH domain) , PF00069 (Protein kinase domain) , PF00130 (Phorbol esters/diacylglycerol binding domain (C1 domain)) (2)contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR001849 (Pleckstrin-like), IPR000719 (Protein kinase, core), IPR015727 (Protein kinase C mu-related), IPR011993 (Pleckstrin homology-type), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
6	Y57A10C.8	Y57A10C.8	n/a	chrII 12,428,881	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR002355 (Multicopper oxidase, copper-binding site)
7	Y43C5A.4	Y43C5A.4	n/a	chrIV 10,278,717	contains similarity to Interpro domain IPR000694 (Proline-rich region)
8	ZK112.6	ZK112.6	n/a	chrIII 7,740,126	contains similarity to Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni Acetyl-coenzyme A synthetase (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-sactivating enzyme).; SW:Q72LY9
9	F35A5.5	F35A5.5	n/a	chrX 3,794,638	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000976 (Wilm's tumour protein)
10	tni-4	W03F8.1	n/a	chrIV 5,205,854	tni-4 encodes one of the four elegans troponin I proteins; tni-4 is required for the normal development of the pharynx during embryonic development; TNI-4 interacts only with the pharyngeal troponin C; tni-4 is expressed exclusively in the pharyngeal muscles.
11	C03A3.3	C03A3.3	n/a	chrX 11,268,134	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)
12	F46F3.3	F46F3.3	n/a	chrV 11,668,418	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q86J27
13	R10E11.5	R10E11.5	n/a	chrIII 9,787,703	contains similarity to Homo sapiens cDNA FLJ77065, highly similar to Homo sapiens golgi autoantigen, golgin subfamily a, 4 (GOLGA4), mRNA; ENSEMBL:ENSP00000349305
14	ZC411.1	ZC411.1	n/a	chrV 8,878,230
15	C11G6.3	C11G6.3	n/a	chrX 16,343,288	contains similarity to Pfam domain PF00628 PHD-finger contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR000956 (Stathmin), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR003026 (Transcription factor Otx1, C-terminal), IPR000533 (Tropomyosin), IPR011011 (Zinc finger, FYVE/PHD-type)
16	C54E10.2	C54E10.2	n/a	chrV 18,829,031	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
17	ugt-32	F47C10.6	n/a	chrV 3,842,918	C. elegans UGT-32 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
18	T21E12.3	T21E12.3	n/a	chrI 4,403,989	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
19	sos-1	T28F12.3	n/a	chrV 4,533,472	The sos-1 gene, also known as let-341, encodes an ortholog of Son of sevenless, a guanine nucleotide exchange factor that affects viability, sex myoblast migration, vulval induction, and oogenesis; it acts genetically downstream of let-23 and upstream of let-60 with respect to vulval development.
20	R57.2	R57.2	n/a	chrX 298,212	contains similarity to Pfam domain PF01682 DB module contains similarity to Interpro domain IPR002602 (Protein of unknown function DB)
21	glb-8	C26C6.7	n/a	chrI 7,510,602	glb-8 encodes a globin with no obvious function in mass RNAi assays; glb-8 expression is induced by anoxia in a HIF-1 dependent manner, although it is also paradoxically upregulated in a hif-1 mutant background; glb-8 expression is downregulated in a daf-2(e1370) mutant background under normoxic conditions; glb-8 expression is lower in L3 larvae than in young adults or dauers.
22	srh-137	Y70C5C.4	n/a	chrV 16,716,048	C. elegans SRH-137 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	Y102A5C.27	Y102A5C.27	n/a	chrV 16,988,446	contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
24	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
25	C44C10.7	C44C10.7	n/a	chrX 11,687,559	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
26	C08H9.6	C08H9.6	n/a	chrII 9,873,847	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
27	C01G12.5	C01G12.5	n/a	chrII 14,586,920	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
28	tsg-101	C09G12.9	n/a	chrIV 3,512,510	C09G12.9 encodes the C. elegans ortholog of S. cerevisiae vacuolar protein sorting protein Vps23p and human TUMOR SUSCEPTIBILITY GENE 101 (TSG101; OMIM:601387), mutations in which are associated with several types of cancer and with varying responses to HIV infection; the product of C09G12.9 is predicted to be a component of C. elegans ESCRT-1 (Endosomal Sorting Complex Required for Transport), and RNAi experiments indicate that its activity is essential for embryonic and larval development.
29	C39B10.5	C39B10.5	n/a	chrX 10,447,468	contains similarity to Saccharomyces cerevisiae bZIP protein; transcription factor; SGD:YIR018W
30	srw-122	H27D07.5	n/a	chrV 2,951,456	C. elegans SRW-122 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
31	C04A11.1	C04A11.1	n/a	chrX 13,661,662	contains similarity to Sorghum bicolor Extensin precursor (Proline-rich glycoprotein).; SW:EXTN_SORBI
32	let-23	ZK1067.1	n/a	chrII 9,202,659	let-23 encodes an EGF-receptor-family transmembrane tyrosine kinase that affects viability, inductive signaling during development of the vulva, male spicule formation, posterior development of the epidermis, ovulation and behavioral quiescience during lethargus; it is genetically upstream of the let-60/RAS pathway with respect to viability and vulval development, is upstream of phosopholipase C gamma with respect to fertility and quiesence, and is expressed in vulval precursor cells and the ALA neuron.
33	Y39A1A.7	Y39A1A.7	n/a	chrIII 10,619,501	contains similarity to Sus scrofa Lymphocyte antigen 64-like protein.; TR:Q7YRL4
34	F22F1.3	F22F1.3	n/a	chrX 8,162,399	contains similarity to Pfam domain PF02172 KIX domain contains similarity to Interpro domain IPR003101 (Coactivator CBP, KIX)
35	C16D9.8	C16D9.8	n/a	chrV 8,262,448
36	srm-1	T28H11.2	n/a	chrIV 5,013,566	C. elegans SRM-1 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001991 (Sodium:dicarboxylate symporter)
37	H10E21.4	H10E21.4	n/a	chrIII 18,471	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR003299 (Flagellar calcium-binding protein (calflagin))
38	nhr-44	T19A5.4	n/a	chrV 8,962,974	C. elegans NHR-44 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
39	T02B11.6	T02B11.6	n/a	chrV 887,079	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
40	T05H4.7	T05H4.7	n/a	chrV 6,416,194	contains similarity to Pfam domain PF00182 Chitinase class I contains similarity to Interpro domain IPR000726 (Glycoside hydrolase, family 19, catalytic)
41	F45C12.3	F45C12.3	n/a	chrII 1,731,227	contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
42	str-178	R11D1.5	n/a	chrV 12,715,427	C. elegans STR-178 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
43	srx-34	T01C4.4	n/a	chrV 7,119,646	C. elegans SRX-34 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
44	che-3	F18C12.1	n/a	chrI 8,071,859	The dynein heavy chain (DHC) 1b isoform that affects the establishment and maintainance of the structural integrity of sensory cilia and also has a role in intraflagellar transport; it is expressed in ciliated sensory neurons.
45	nhr-4	F32B6.1	n/a	chrIV 9,880,614	nhr-4 is predicted to encode a nuclear hormone receptor (NHR); expression may peak during the late larval stages, based on mRNA expression analysis.
46	fpn-1.3	R08F11.6	n/a	chrV 3,796,213	C. elegans FPN-1.3 protein; contains similarity to Pfam domain PF06963 Ferroportin1 (FPN1) contains similarity to Interpro domains IPR009716 (Ferroportin1), IPR016196 (MFS general substrate transporter)
47	F15A4.5	F15A4.5	n/a	chrII 12,470,242	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8ICX2
48	srv-7	T22B7.5	n/a	chrX 5,643,888	C. elegans SRV-7 protein; contains similarity to Interpro domain IPR000832 (GPCR, family 2, secretin-like)
49	F19G12.2	F19G12.2	n/a	chrX 1,429,318	contains similarity to Pfam domain PF00268 Ribonucleotide reductase, small chain contains similarity to Interpro domains IPR012348 (Ribonucleotide reductase-related), IPR000358 (Ribonucleotide reductase), IPR009078 (Ferritin/ribonucleotide reductase-like)
50	B0554.5	B0554.5	n/a	chrV 425,501	contains similarity to Pfam domain PF05978 Eukaryotic protein of unknown function (DUF895) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR016196 (MFS general substrate transporter)