UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	C35B1.4	C35B1.4	6e-56	chrIV 4,079,997
2	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
3	K07A1.6	K07A1.6	n/a	chrI 9,592,533	K07A1.6 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; K07A1.6 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; K07A1.6 has no obvious function in mass RNAi assays.
4	F22B3.4	F22B3.4	n/a	chrIV 11,411,714	F22B3.4 encodes a putative glucosamine-fructose 6-phosphate aminotransferase, paralogous to F07A11.2, thought to catalyse the first step of the hexosamine pathway to UDP-N-acetylglucosamine or UDP-N-acetylgalactosamine; F22B3.4 transcripts are enriched during oogenesis; F22B3.4(RNAi) animals have an osmotically-sensitive embryonic lethal phenotype, presumably because of defects in chitin and eggshell synthesis.
5	F55B11.2	F55B11.2	n/a	chrIV 14,422,746	contains similarity to Xenopus laevis Similar to LGN protein.; TR:Q8AVU7
6	oma-2	ZC513.6	n/a	chrV 8,030,304	The oma-2 gene encodes a zinc finger protein of the TIS11 finger type that is paralogous to OMA-1; while either oma-1 or oma-2 individually have no obvious mutant phenotype, a normal copy of at least one of these genes is required for oocyte maturation.
7	puf-5	F54C9.8	n/a	chrII 8,576,562	C. elegans PUF-5 protein; contains similarity to Pfam domain PF00806 Pumilio-family RNA binding repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR001313 (Pumilio RNA-binding region), IPR016024 (Armadillo-type fold)
8	B0513.4	B0513.4	n/a	chrIV 13,880,800	contains similarity to Ixodes scapularis Putative secreted protein.; TR:Q8MVF5
9	dod-23	F49E12.2	n/a	chrII 8,398,700	C. elegans DOD-23 protein ;
10	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
11	W05F2.3	W05F2.3	n/a	chrI 3,368,102
12	Y62H9A.4	Y62H9A.4	n/a	chrX 11,880,601	contains similarity to Branchiostoma floridae Homeobox protein DLL homolog.; SW:HMDL_BRAFL
13	C25A8.4	C25A8.4	n/a	chrIV 7,006,427	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
14	T21C9.13	T21C9.13	n/a	chrV 10,597,963	contains similarity to Fusobacterium nucleatum Branched chain amino acid transport system II carrier protein.; TR:Q8REN9
15	Y62H9A.6	Y62H9A.6	n/a	chrX 11,883,508	contains similarity to Brucella melitensis Hypothetical cytosolic protein BMEI0237.; TR:Q8YJ49
16	T01H3.4	T01H3.4	n/a	chrII 7,881,603	T01H3.4 encodes an unfamiliar protein; T01H3.4 and T01H3.5 share an operon divergently transcribed from another operon containing vha-4.
17	cpg-3	R06C7.4	n/a	chrI 7,245,503	cgp-3 encodes a putatively secreted protein with an N-terminal low-complexity domain containing 15 potential chondroitin attachment sites, and a C-terminal EGF-like region; cpg-3 mRNA is enriched in oogenesis, but CPG-3 has no obvious function in mass RNAi assays.
18	W02D9.6	W02D9.6	n/a	chrI 12,560,492	contains similarity to Homo sapiens similar to KIAA1107 protein; ENSEMBL:ENSP00000176186
19	F17E9.4	F17E9.4	n/a	chrIV 8,348,753
20	C28C12.2	C28C12.2	n/a	chrIV 8,499,682
21	clec-61	ZK666.7	n/a	chrII 10,489,551	C. elegans CLEC-61 protein; contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002035 (von Willebrand factor, type A)
22	D1054.11	D1054.11	n/a	chrV 10,794,334	contains similarity to Interpro domain IPR000104 (Antifreeze protein, type I)
23	C14B1.2	C14B1.2	n/a	chrIII 3,702,706	contains similarity to Bacillus anthracis Hypothetical protein.; TR:Q81T15
24	mei-2	F57B10.12	n/a	chrI 6,565,308	mei-2 encodes a novel protein that contains a region similar to the p80-targeting subunit of katanin that is required for embryonic viability, alignment of chromosomes at the metaphase plate, and establishment of the oocyte meiotic spindle together with MEI-1; can interact with MEI-1 in HeLa cells and this complex can function to disassemble microtubules, expressed in the germ line, throughout the cytoplasm of most mature oocytes within the proximal gonad, and localization is mutually dependent upon MEI-1
25	gln-5	F26D10.10	n/a	chrIV 17,272,909	C. elegans GLN-5 protein; contains similarity to Pfam domains PF03951 (Glutamine synthetase, beta-Grasp domain) , PF00120 (Glutamine synthetase, catalytic domain) contains similarity to Interpro domains IPR008147 (Glutamine synthetase, beta-Grasp), IPR014746 (Glutamine synthetase/guanido kinase, catalytic region), IPR008146 (Glutamine synthetase, catalytic region)
26	T27A10.6	T27A10.6	n/a	chrX 3,592,684	contains similarity to Interpro domain IPR006150 (Cysteine-rich repeat)
27	W02D9.7	W02D9.7	n/a	chrI 12,559,462	contains similarity to Vibrio vulnificus Septum formation inhibitor-activating ATPase.; TR:Q8DFS3
28	vit-1	K09F5.2	n/a	chrX 7,730,476	C. elegans VIT-1 protein; contains similarity to Pfam domains PF00094 (von Willebrand factor type D domain) , PF09172 (Domain of unknown function (DUF1943)) , PF01347 (Lipoprotein amino terminal region) contains similarity to Interpro domains IPR015819 (Lipid transport protein, beta-sheet shell), IPR011030 (Vitellinogen, superhelical), IPR015818 (Vitellinogen, open beta-sheet, subdomain 2), IPR001747 (Lipid transport protein, N-terminal), IPR015816 (Vitellinogen, beta-sheet N-terminal), IPR001846 (von Willebrand factor, type D), IPR015255 (Vitellinogen, open beta-sheet)
29	tbh-1	H13N06.6	n/a	chrX 15,501,790	tbh-1 encodes a putative dopamine beta-hydroxylate orthologous to human DBH (OMIM:609312, mutated in dopamine beta-hydroxylase deficiency).
30	C23G10.11	C23G10.11	n/a	chrIII 6,215,297	contains similarity to Interpro domain IPR003059 (Colicin lysis protein)
31	F54F7.3	F54F7.3	n/a	chrX 11,849,694	contains similarity to Amsacta moorei entomopoxvirus AMV135.; TR:Q9EMR4
32	vit-5	C04F6.1	n/a	chrX 3,406,006	vit-5 encodes a vitellogenin, a lipid-binding protein precursor related to vertebrate vitellogenins and mammalian ApoB-100, a core LDL particle constituent; by homology, VIT-5 is predicted to function as a lipid transport protein; loss of vit-5 activity via large-scale RNA-mediated interference (RNAi) screens indicates that VIT-5 is required for embryogenesis and normal rates of postembryonic growth; VIT-5 is a major yolk component and is expressed exclusively in the adult hermaphrodite intestine from which it is secreted into the pseudocoelomic space and taken up by oocytes.
33	F57C2.4	F57C2.4	n/a	chrII 14,525,575	contains similarity to Homo sapiens Crumbs protein homolog 1 precursor; ENSEMBL:ENSP00000256772
34	C44B7.5	C44B7.5	n/a	chrII 6,871,922	contains similarity to Interpro domain IPR005018 (DOMON related)
35	F48E3.4	F48E3.4	n/a	chrX 7,494,618	contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR009003 (Peptidase, trypsin-like serine and cysteine)
36	C53B7.2	C53B7.2	n/a	chrX 6,846,844	C53B7.2 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; C53B7.2 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; C53B7.2 has no obvious function in mass RNAi assays.
37	C17E4.3	C17E4.3	n/a	chrI 9,417,878	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
38	F49E12.1	F49E12.1	n/a	chrII 8,402,502	contains similarity to Pfam domains PF01549 (ShK domain-like) , PF03098 (Animal haem peroxidase) contains similarity to Interpro domains IPR010255 (Haem peroxidase), IPR002007 (Haem peroxidase, animal), IPR003582 (Metridin-like ShK toxin)
39	T01C3.3	T01C3.3	n/a	chrV 14,992,169	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
40	C17G1.2	C17G1.2	n/a	chrX 9,922,096	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IJE7
41	C49F5.7	C49F5.7	n/a	chrX 11,995,234	contains similarity to Homo sapiens Similar to PDZ domain proteins; ENSEMBL:ENSP00000298474
42	cpg-2	B0280.5	n/a	chrIII 7,102,966	cpg-2 encodes a protein with six chitin-binding peritrophin-A domains and three mucin-like regions; CPG-2 is individually dispensable for normal embryonic development; however, CPG-2 and CPG-1 are jointly required for osmotic integrity of early embryos, error-free chromosomal segregation during meiosis, polar body extrusion, association of the sperm pronucleus/centrosome complex (SPCC) with the early embryonic cortex, localization of PAR-2 in early embryos, posterior localization of P granules or PIE-1, and pseudocleavage; CPG-2, like CPG-1, is covalently linked to chondroitin, which itself is required for vulval morphogenesis, polar-body extrusion, and separation of the eggshell from the embryonic plasma membrane; cpg-2 mRNA, like that of cpg-1, is expressed specifically in the adult hermaphrodite germ line and is bound by GLD-1; CPG-2 has 34 potential chondroitin attachment sites, four of them verified by mass spectrometry, and transgenic CPG-2 synthesized in mammalian cells carries chondroitin sulfate chains; CPG-2's multiple peritrophin-A domains may enable mechanical cross-linking of chitin.
43	spp-18	F27C8.4	n/a	chrIV 9,594,036	C. elegans SPP-18 protein; contains similarity to Interpro domains IPR011001 (Saposin-like), IPR000480 (Glutelin), IPR008139 (Saposin B)
44	C10G8.4	C10G8.4	n/a	chrV 5,312,109	C10G8.4 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; C10G8.4 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; C10G8.4 has no obvious function in mass RNAi assays.
45	Y37D8A.19	Y37D8A.19	n/a	chrIII 12,930,534	contains similarity to Hordeum vulgare Nonspecific lipid-transfer protein 4.3 precursor (LTP 4.3).; SW:NL43_HORVU
46	EEED8.3	EEED8.3	n/a	chrII 5,414,802	EEED8.3 encodes a protein with similarity to fatty acid-binding proteins; loss of EEED8.3 activity via RNAi results in 20-30% embryonic lethality.
47	pos-1	F52E1.1	n/a	chrV 8,414,649	pos-1 encodes a CCCH-type zinc-finger protein; during embryogenesis, maternally provided POS-1 is essential for proper fate specification of germ cells, intestine, pharynx, and hypodermis; POS-1's role in cell fate specification is likely as a translational regulator, as POS-1 is required, in posterior blastomeres, for positive regulation of apx-1 mRNA translation and negative regulation of glp-1 mRNA translation via direct binding to the spatial control region (SCR) in the glp-1 mRNA 3' UTR; in regulating mRNA translation, POS-1 interacts with SPN-4, an RNP-type RNA binding protein, that may function to negatively regulate POS-1 activity; pos-1 mRNA is first detected in the gonads of L4 and adult animals, and is present uniformly in oocytes and newly fertilized embryos; during early embryonic divisions, pos-1 mRNA is present at higher levels in germline blastomeres until it disappears following the division of P4; POS-1 protein is first apparent at low levels in 1-cell embryos, with subsequent expression mirroring that of pos-1 mRNA: high levels in germline blastomeres until its disappearance after the P4 division; in the germline blastomeres P1, P2, P3, and P4, POS-1 colocalizes with cytoplasmic and perinuclear P granules.
48	F56H9.2	F56H9.2	n/a	chrV 12,637,872	contains similarity to Plasmodium falciparum Transport protein, putative.; TR:Q8IHR3
49	Y45F10C.4	Y45F10C.4	n/a	chrIV 13,663,763	contains similarity to Pfam domain PF07403 Protein of unknown function (DUF1505) contains similarity to Interpro domain IPR009981 (Protein of unknown function DUF1505)
50	T05F1.2	T05F1.2	n/a	chrI 9,623,710	T05F1.2 encodes a novel protein; in situ hybridization studies indicate that T05F1.2 mRNA is expressed in the medial germline.