UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nhr-139	C33G8.8	0	chrV 6,986,930	C. elegans NHR-139 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
2	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
3	str-171	T01G5.5	n/a	chrV 15,131,482	C. elegans STR-171 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
4	grk-1	F19C6.1	n/a	chrX 9,995,164	grk-1 encodes a serine/threonine protein kinase that is most closely related to G protein-coupled receptor (GPCR) kinases.
5	srd-4	ZK863.5	n/a	chrV 12,185,574	C. elegans SRD-4 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
6	srv-33	T13A10.13	n/a	chrIV 6,283,633	C. elegans SRV-33 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
7	C50H2.4	C50H2.4	n/a	chrV 9,917,432	contains similarity to Arabidopsis thaliana Putative cytochrome P450.; TR:Q9LQ26
8	tag-199	F45E4.4	n/a	chrIV 7,612,783	C. elegans TAG-199 protein ; contains similarity to Trypanosoma brucei Putative uncharacterized protein.; TR:Q4GZ45
9	ttm-2	F26G1.4	n/a	chrII 4,765,267	C. elegans TTM-2 protein; contains similarity to Pfam domain PF00339 Arrestin (or S-antigen), N-terminal domain contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011021 (Arrestin-like, N-terminal)
10	pap-1	Y32F6A.3	n/a	chrV 10,444,197	pap-1 encodes a poly (A) polymerase; large-scale RNAi screens indicate that PAP-1 activity is essential for reproduction, embryonic and larval development, proper body morphology, normal rates of growth, and coordinated locomotion.
11	T26H5.8	T26H5.8	n/a	chrV 15,429,911	contains similarity to Pfam domains PF04789 (Protein of unknown function (DUF621)) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR006874 (Protein of unknown function DUF621)
12	col-37	ZK863.2	n/a	chrV 12,167,206	col-37 encodes a cuticle collagen.
13	C16A3.6	C16A3.6	n/a	chrIII 6,379,994	contains similarity to Pfam domain PF04874 Mak16 protein contains similarity to Interpro domain IPR006958 (Mak16 protein)
14	C07D10.1	C07D10.1	n/a	chrII 7,399,714	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
15	K02A11.3	K02A11.3	n/a	chrI 9,746,967	contains similarity to Homo sapiens Placental protein 11 precursor; ENSEMBL:ENSP00000229003
16	B0304.2	B0304.2	n/a	chrII 4,524,073
17	Y40H7A.11	Y40H7A.11	n/a	chrIV 15,219,977	contains similarity to Interpro domain IPR006629 (LPS-induced tumor necrosis factor alpha factor)
18	T28F4.4	T28F4.4	n/a	chrI 7,488,371	contains similarity to Brugia malayi Putative uncharacterized protein BMBAC01P19.05a.; TR:Q8IHI4
19	C15B12.2	C15B12.2	n/a	chrX 6,464,379
20	hex-1	T14F9.3	n/a	chrX 2,225,047	hex-1 encodes a beta-N-acetylhexosaminidase that is orthologous to the human gene CERVICAL CANCER PROTO-ONCOGENE 7 (HEXB; OMIM:606873), which when mutated leads to disease.
21	F45C12.16	F45C12.16	n/a	chrII 1,737,908	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
22	srx-84	F35B12.1	n/a	chrV 11,599,872	C. elegans SRX-84 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
23	F31C3.5	F31C3.5	n/a	chrI 15,053,308	contains similarity to Pfam domain PF04128 Partner of SLD five, PSF2 contains similarity to Interpro domains IPR016906 (GINS complex, PSF2 component, subgroup), IPR007257 (GINS complex, Psf2 component)
24	K07C11.3	K07C11.3	n/a	chrV 8,207,597	contains similarity to Interpro domains IPR008993 (TIMP-like, OB-fold), IPR001820 (Proteinase inhibitor I35, tissue inhibitor of metalloproteinase), IPR001134 (Netrin, C-terminal)
25	ZK673.4	ZK673.4	n/a	chrII 10,453,965	ZK673.4 encodes a protein with a THAP or THAP-like domain; other proteins with such domains include LIN-15A, LIN-15B, LIN-36, and HIM-17 (which all interact with LIN-35/Rb), as well as CDC-14B, CTB-1, GON-14, and ~100 other proteins such as Drosophila P element transposase and human nuclear proapoptotic factor THAP1.
26	dnj-4	C01G8.4	n/a	chrI 5,283,025	This gene encodes a protein containing a DnaJ ('J') domain.
27	fbxa-69	F54B8.3	n/a	chrV 15,815,021	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
28	H43I07.1	H43I07.1	n/a	chrV 4,206,564	contains similarity to Interpro domains IPR010754 (Optic atrophy 3-like), IPR005819 (Histone H5)
29	C47D12.5	C47D12.5	n/a	chrII 11,685,843
30	try-2	C07G1.1	n/a	chrIV 8,213,133	try-2 encodes a homolog of human TRYP1 and ELA2; mutation of human TRYP1 or ELA2 leads, respectively, to hereditary pancreatitis (OMIM:276000) or cyclic haematopoiesis (OMIM:162800).
31	Y57G11C.20	Y57G11C.20	n/a	chrIV 14,844,297	contains similarity to Interpro domain IPR000003 ()
32	B0545.4	B0545.4	n/a	chrIV 109,498	contains similarity to Pfam domain PF05699 hAT family dimerisation domain contains similarity to Interpro domain IPR008906 (HAT dimerisation)
33	ptr-16	T21H3.2	n/a	chrV 1,172,902	ptr-16 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-16 is partially required for normal molting from L2 to L3 larval stages; however, PTR-16 and PTR-1 together are strongly required for both molting and viability, with double ptr-1/-16 RNAi animals showing pronounced molting defects and lethality; PTR-16 is also required for normal growth to full size and locomotion.
34	spp-6	T08A9.10	n/a	chrX 7,317,449	spp-6 encodes a predicted transmembrane protein containing a saposin (B) domain that is a member of a saposin-like protein superfamily containing mammalian NK-lysin and granulysin and the protozoan amoebapores; SPP-6 is predicted to function as a lipid-binding protein that may possess pore-forming, cytotoxic activity; as loss of SPP-6 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of SPP-6 in C. elegans development and/or behavior is not yet known.
35	str-227	C07G3.3	n/a	chrV 3,518,993	C. elegans STR-227 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	nhr-269	R08H2.9	0.0008	chrV 15,369,318	C. elegans NHR-269 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
37	T19H5.1	T19H5.1	n/a	chrII 9,473,432	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
38	K08D8.1	K08D8.1	n/a	chrIV 12,893,458	contains similarity to Fusobacterium nucleatum Tryptophanase (EC 4.1.99.1).; TR:Q8RHQ6
39	fbxb-35	F07E5.2	n/a	chrII 2,052,208	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
40	nhr-37	F44C4.2	0.0000006	chrV 6,623,464	C. elegans NHR-37 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
41	T13F2.6	T13F2.6	n/a	chrIV 9,779,719
42	ref-1	T01E8.2	n/a	chrII 10,219,169	ref-1 encodes a protein with two basic helix-loop-helix (bHLH) domains that is distantly related to the hairy/Enhancer of split subfamily of bHLH transcription factors; REF-1 is required in hermaphrodites during early larval development for regulating the pattern of posterior Pn.p hypodermal cell fusions, primarily through regulation of MAB-5 homeodomain protein activity; REF-1 is also required for head morphogenesis and specification of the V6 lateral seam cell fate; in males, ref-1 is a target of MAB-3 transcriptional repression which in turn, promotes expression of LIN-32, a proneural bHLH transcription factor.
43	acbp-5	T12D8.3	n/a	chrIII 13,640,695	C. elegans ACBP-5 protein; contains similarity to Pfam domains PF00023 (Ankyrin repeat) (2), PF00887 (Acyl CoA binding protein) contains similarity to Interpro domains IPR014352 (FERM/acyl-CoA-binding protein, 3-helical bundle), IPR002110 (Ankyrin), IPR000582 (Acyl-CoA-binding protein, ACBP)
44	F58H7.5	F58H7.5	n/a	chrIV 920,399
45	C05D11.13	C05D11.13	n/a	chrIII 6,443,485	contains similarity to Drosophila melanogaster Flybase gene name is CG2839-PA;; FLYBASE:CG2839
46	ZK930.2	ZK930.2	n/a	chrII 11,892,790	contains similarity to Interpro domain IPR010989 (t-SNARE)
47	grl-3	K03B8.7	n/a	chrV 11,411,850	grl-3 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-3 is expressed in intestine, larval renal gland cells, and larval neurons; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
48	col-43	ZC513.8	n/a	chrV 8,050,298	col-43 encodes a collagen that is individually dispensable for viability and gross morphology in mass RNAi screens.
49	R11G1.2	R11G1.2	n/a	chrX 3,653,706
50	F08F1.3	F08F1.3	n/a	chrX 8,430,035