UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	str-74	C14H10.4	4e-177	chrX 10,240,354	C. elegans STR-74 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
2	F44E5.2	F44E5.2	n/a	chrII 11,770,321	contains similarity to Pfam domain PF00560 Leucine Rich Repeat
3	taf-11.3	F43D9.5	n/a	chrIII 10,504,535	The taf-11.3 gene encodes an ortholog of human TATA-binding protein associated factor TAF11 (TAFII28, OMIM:600772) that is a component of the TFIID general transcription factor that recognizes the transcription start site; TAF-11.3 is required for proper post-embryonic development.
4	F20H11.6	F20H11.6	n/a	chrIII 6,599,869
5	cdc-48.3	K04G2.3	n/a	chrI 8,034,273	C. elegans CDC-48.3 protein; contains similarity to Pfam domains PF07726 (ATPase family associated with various cellular activities (AAA)) , PF00004 (ATPase family associated with various cellular activities (AAA)) , PF07728 (ATPase family associated with various cellular activities (AAA)) contains similarity to Interpro domains IPR003959 (AAA ATPase, core), IPR011704 (ATPase associated with various cellular activities, AAA-5), IPR011703 (ATPase associated with various cellular activities, AAA-3), IPR003960 (AAA ATPase, conserved site), IPR003593 (AAA+ ATPase, core)
6	srh-233	Y113G7A.1	n/a	chrV 20,046,361	C. elegans SRH-233 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
7	Y45F10D.4	Y45F10D.4	n/a	chrIV 13,784,287	Y45F10D.4 encodes a putative iron-sulfur cluster assembly enzyme that is required for embryonic and larval viability, and that is orthologous to human NIFUN and budding yeast ISU1 and ISU2; Y45F10D.4 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults; by orthology with yeast ISU1, Y45F10D.4 is predicted to bind FRH-1.
8	F44E5.3	F44E5.3	n/a	chrII 11,763,830	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000304160
9	E02H9.4	E02H9.4	n/a	chrIII 2,457,255	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domain IPR004987 (Protein of unknown function DUF272)
10	str-55	F26D2.7	1e-58	chrV 16,416,377	C. elegans STR-55 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	dylt-3	T05C12.5	n/a	chrII 8,181,777	dylt-3 encodes a putative dynein light chain subunit paralogous to DYLT-3, and orthologous to human DYNLT1 and DYNLT3 (OMIM: 300302); unlike its paralog DYLT-1, DYLT-3 does not obviously inhibit DHC-1 in vivo.
12	eat-5	F13G3.8	n/a	chrI 7,310,218	eat-5 encodes an innexin, expressed in pharyngeal muscle cell groups pm4 and pm5, that is required for synchronized pharyngeal muscle contractions, and for normal electrical connections between pharyngeal muscle cells; EAT-5 forms electrically permeable intercellular channels (gap junctions), with a predicted membrane topology analogous to that of connexins, which affects electrical coupling between different parts of the pharynx and thus affects feeding.
13	C02H6.1	C02H6.1	n/a	chrV 7,389,111	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
14	Y39E4B.7	Y39E4B.7	n/a	chrIII 13,113,204	contains similarity to Pfam domain PF01529 (DHHC zinc finger domain)
15	F53H4.3	F53H4.3	n/a	chrX 15,886,572	contains similarity to Mus musculus Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).; SW:ATX1_MOUSE
16	srx-13	C44B12.4	n/a	chrIV 1,116,817	C. elegans SRX-13 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
17	T02G6.6	T02G6.6	n/a	chrI 11,821,054	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
18	twk-3	M110.2	n/a	chrII 8,211,638	C. elegans TWK-3 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
19	srh-113	Y68A4A.7	n/a	chrV 17,213,595	C. elegans SRH-113 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	Y76G2A.2	Y76G2A.2	n/a	chrI 5,979,210
21	lin-1	C37F5.1	n/a	chrIV 2,288,106	lin-1 encodes an Ets-domain-containing transcription factor that is a member of the ETS gene family that includes human ELK1, 3, and 4 (OMIM:600247); LIN-1 functions as a general effector of MAP kinase-mediated signaling; when MAP kinase is inactive, LIN-1 forms a complex with LIN-31/WH that inhibits vulval cell fate specification; upon MAP kinase activation (vulval induction), LIN-1 is phosphorylated, dissociates from LIN-31, and becomes inactive, thus allowing for vulval development.
22	C10E2.4	C10E2.4	n/a	chrX 16,750,349
23	F14D2.5	F14D2.5	n/a	chrII 3,340,796
24	T14G10.8	T14G10.8	n/a	chrIV 10,146,609	contains similarity to Homo sapiens Splice isoform 1 of P08235 Mineralocorticoid receptor; ENSEMBL:ENSP00000281330
25	F19G12.3	F19G12.3	n/a	chrX 1,425,941	contains similarity to Pfam domain PF02170 PAZ domain contains similarity to Interpro domain IPR003100 (Argonaute and Dicer protein, PAZ)
26	srh-48	C06C3.6	n/a	chrII 9,384,056	C. elegans SRH-48 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	str-134	C05E4.6	0.0005	chrV 744,563	C. elegans STR-134 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	srw-53	T05G11.7	n/a	chrV 15,944,112	C. elegans SRW-53 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300)
29	srw-94	H06H21.1	n/a	chrIV 4,815,890	C. elegans SRW-94 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
30	K02E7.4	K02E7.4	n/a	chrII 1,073,572	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domain IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
31	srh-97	F49H6.4	n/a	chrV 17,018,412	C. elegans SRH-97 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	Y52B11A.9	Y52B11A.9	n/a	chrI 11,036,452	contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR005824 (KOW), IPR002358 (Ribosomal protein L6, conserved site-1), IPR007087 (Zinc finger, C2H2-type)
33	C33C12.9	C33C12.9	n/a	chrII 2,188,303	contains similarity to Pfam domain PF05175 Methyltransferase small domain contains similarity to Interpro domains IPR007848 (Methyltransferase small), IPR004557 (Putative methylase), IPR002296 (N6 adenine-specific DNA methyltransferase, N12 class), IPR002052 (N-6 adenine-specific DNA methylase, conserved site)
34	R119.5	R119.5	n/a	chrI 391,462	contains similarity to Pfam domain PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) contains similarity to Interpro domain IPR000682 (Protein-L-isoaspartate(D-aspartate) O-methyltransferase)
35	D2013.3	D2013.3	n/a	chrII 9,318,488	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
36	C34B2.9	C34B2.9	n/a	chrI 10,701,670	contains similarity to Interpro domain IPR001904 (Paxillin)
37	grl-18	T05C3.4	n/a	chrV 5,487,265	grl-18 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
38	Y63D3A.8	Y63D3A.8	n/a	chrI 14,116,402	contains similarity to Interpro domains IPR002114 (Phosphotransferase system, HPr serine phosphorylation site), IPR006634 (TRAM, LAG1 and CLN8 homology)
39	F58F6.3	F58F6.3	n/a	chrIV 1,375,965
40	Y17D7B.5	Y17D7B.5	n/a	chrV 18,775,675	contains similarity to Interpro domain IPR006583 (CW)
41	ZK856.11	ZK856.11	n/a	chrV 10,204,273	contains similarity to Pfam domain PF01176 Translation initiation factor 1A / IF-1 contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR006196 (S1, IF1 type), IPR001253 (Eukaryotic initiation factor 1A (eIF-1A))
42	srh-281	F11A5.1	n/a	chrV 16,191,496	C. elegans SRH-281 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
43	srh-222	F47C12.10	n/a	chrIV 3,980,509	C. elegans SRH-222 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	srd-68	F09C6.7	n/a	chrV 16,901,990	C. elegans SRD-68 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	sre-40	T05A7.8	n/a	chrII 4,682,734	C. elegans SRE-40 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
46	C14B1.5	C14B1.5	n/a	chrIII 3,708,022	C14B1.5 encodes an ortholog of S. cerevisiae YIL103 and human DPH2L1/OVCA1 (OMIM:603527, deleted or downregulated in ovarian tumors); C14B1.5 is paralogous to S. cerevisiae DPH2/YKL191W, a protein component of diphtamide synthesis; C14B1.5 has no obvious function in mass RNAi assays.
47	W06G6.9	W06G6.9	n/a	chrV 16,646,169	contains similarity to Ralstonia solanacearum Hypothetical protein RSc2317.; TR:Q8XX01
48	F44G3.10	F44G3.10	n/a	chrV 16,139,209	F44G3.10 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F44G3.10 is worm-specific, with obvious homologs only in C. elegans; F44G3.10 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
49	F02E11.4	F02E11.4	n/a	chrII 3,276,774	contains similarity to Interpro domain IPR002625 (Smr protein/MutS2 C-terminal)
50	C50E3.2	C50E3.2	n/a	chrV 7,610,647	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)