UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srsx-11	C13D9.4	6e-170	chrV 4,978,533	C. elegans SRSX-11 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
2	F26D2.15	F26D2.15	n/a	chrV 16,438,363	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
3	fkh-10	C25A1.2	n/a	chrI 10,164,375	fkh-10 encodes one of 15 forkhead transcriptional regulators encoded by the C. elegans genome; by homology, FKH-10 is predicted to function as a transcription factor that regulates gene expression during development; however, as loss of fkh-10 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of FKH-10 in C. elegans development and/or behavior is not yet known; nevertheless, reporter gene studies indicate that throughout larval and adult stages, fkh-10 expression is detected almost exclusively in six pairs of neuronal nuclei near the terminal bulb of the pharynx, suggesting that FKH-10 may have a specific function in neuronal differentiation.
4	T08G5.1	T08G5.1	n/a	chrV 14,019,744	contains similarity to Saccharomyces cerevisiae Protein that may function as a cochaperone, as suggested by the presence of a DnaJ-like domain; SGD:YNL227C
5	F36F12.8	F36F12.8	n/a	chrV 2,091,148	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
6	C13A2.5	C13A2.5	n/a	chrV 7,277,113	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
7	ver-1	T17A3.1	n/a	chrIII 160,182	C. elegans VER-1 protein; contains similarity to Pfam domains PF00047 (Immunoglobulin domain) (2), PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF07679 (Immunoglobulin I-set domain) (2)contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR013098 (Immunoglobulin I-set), IPR011009 (Protein kinase-like), IPR009134 (Vascular endothelial growth factor receptor, VEGFR, N-terminal), IPR003596 (Immunoglobulin V-set, subgroup), IPR013783 (Immunoglobulin-like fold), IPR000719 (Protein kinase, core), IPR007110 (Immunoglobulin-like), IPR003599 (Immunoglobulin subtype), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR013151 (Immunoglobulin)
8	T14E8.2	T14E8.2	n/a	chrX 6,542,867	contains similarity to Interpro domain IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich)
9	srt-73	T06C10.2	n/a	chrIV 7,880,158	C. elegans SRT-73 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
10	C24H10.1	C24H10.1	n/a	chrX 5,073,103	C24H10.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; C24H10.1 is worm-specific, with obvious homologs only in C. elegans; C24H10.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
11	R13.2	R13.2	n/a	chrIV 10,826,996	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
12	C07B5.6	C07B5.6	n/a	chrX 9,520,189	contains similarity to Helicobacter pylori Hypothetical protein HP1327.; TR:O25885
13	srx-7	C14C6.1	n/a	chrV 561,828	C. elegans SRX-7 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
14	F20B6.7	F20B6.7	n/a	chrX 4,207,129
15	M01G12.7	M01G12.7	n/a	chrI 12,115,167	contains similarity to Arabidopsis thaliana Hypothetical protein.; TR:Q9LZ50
16	srh-228	C35D6.1	n/a	chrIV 16,340,479	C. elegans SRH-228 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	srw-142	H05B21.3	n/a	chrV 2,957,658	C. elegans SRW-142 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
18	mnm-2	C10A4.8	n/a	chrX 7,423,795	C. elegans MNM-2 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
19	acr-9	C40C9.2	n/a	chrX 13,644,544	acr-9 encodes a predicted member of the alpha subunit family of nicotinic acetylcholine receptors.
20	ugt-6	ZC455.4	n/a	chrV 12,796,799	C. elegans UGT-6 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
21	age-1	B0334.8	n/a	chrII 11,523,196	age-1 encodes the C. elegans ortholog of the phosphoinositide 3-kinase (PI3K) p110 catalytic subunit; AGE-1, supplied maternally and embryonically, is a central component of the C. elegans insulin-like signaling pathway, lying downstream of the DAF-2/insulin receptor and upstream of both the PDK-1 and AKT-1/AKT-2 kinases and the DAF-16 forkhead type transcription factor, whose negative regulation is the key output of the insulin signaling pathway; in accordance with its role in insulin signaling, AGE-1 activity is required for regulation of metabolism, life span, dauer formation, stress resistance, salt chemotaxis learning, fertility, and embryonic development; although the age-1 expression pattern has not yet been reported, ectopic expression studies indicate that pan-neuronal age-1 expression is sufficient to rescue life-span defects, while neuronal, intestinal, or muscle expression can partially rescue dauer formation, and neuronal or muscle expression can rescue metabolic defects.
22	fbxb-111	F08D12.11	n/a	chrII 2,774,479	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
23	clec-227	F08H9.5	n/a	chrV 14,473,432	C. elegans CLEC-227 protein; contains similarity to Pfam domains PF00431 (CUB domain) (2), PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
24	JC8.4	JC8.4	n/a	chrIV 13,243,908	contains similarity to Pfam domain PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region contains similarity to Interpro domains IPR016192 (APOBEC/CMP deaminase, zinc-binding), IPR002125 (CMP/dCMP deaminase, zinc-binding), IPR016193 (Cytidine deaminase-like)
25	T26E4.1	T26E4.1	n/a	chrV 15,780,361	contains similarity to Pfam domain PF01030 (Receptor L domain)
26	srw-112	K12D9.9	n/a	chrV 3,005,101	C. elegans SRW-112 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
27	srg-16	F15A4.4	n/a	chrII 12,468,465	C. elegans SRG-16 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
28	F19B10.6	F19B10.6	n/a	chrII 3,663,696
29	T24E12.2	T24E12.2	n/a	chrII 3,783,547
30	srw-57	F36G9.1	n/a	chrV 15,954,286	C. elegans SRW-57 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR000276 (GPCR, rhodopsin-like)
31	srz-53	Y102A5C.23	n/a	chrV 16,977,768	C. elegans SRZ-53 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
32	F35G12.7	F35G12.7	n/a	chrIII 4,586,958	contains similarity to Pfam domain PF03091 CutA1 divalent ion tolerance protein contains similarity to Interpro domains IPR004323 (Divalent ion tolerance protein, CutA1), IPR011322 (Nitrogen regulatory PII-like, alpha/beta)
33	C53B4.6	C53B4.6	n/a	chrIV 8,985,786	contains similarity to Pfam domain PF08449 UAA transporter family contains similarity to Interpro domain IPR013657 (UAA transporter)
34	ZK666.1	ZK666.1	n/a	chrII 10,471,061	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q8T282
35	fbxa-89	Y75B8A.21	n/a	chrIII 12,237,580	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
36	ceh-30	C33D12.7	n/a	chrX 3,064,554	ceh-30 encodes a homeodomain protein most similar to Drosophila and mammalian BarH1 (OMIM:605211) which function in neuronal cell fate determination; the precise biological role of CEH-30 in C. elegans development and/or behavior is not yet known.
37	fbxb-108	F08D12.6	n/a	chrII 2,766,099	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
38	T22D1.6	T22D1.6	n/a	chrIV 6,899,771
39	B0244.5	B0244.5	n/a	chrIII 5,745,987
40	F40G12.4	F40G12.4	n/a	chrV 14,268,178	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
41	fbxb-34	W08F4.2	n/a	chrII 589,015	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
42	srt-61	T27C10.1	n/a	chrI 10,905,441	C. elegans SRT-61 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
43	srh-49	C10G11.4	n/a	chrI 6,298,750	C. elegans SRH-49 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	H01M10.2	H01M10.2	n/a	chrX 2,585,134	contains similarity to Interpro domain IPR006220 (Anthranilate synthase component II/delta crystallin)
45	cnk-1	R01H10.8	n/a	chrIII 10,274,812	cnk-1 encodes a protein that contains a SAM domain, a PDZ domain, and a PH domain.
46	tax-2	F36F2.5	n/a	chrI 9,023,241	tax-2 is orthologous to the human gene ROD PHOTORECEPTOR CNG-CHANNEL BETA SUBUNIT (CNGB1; OMIM:600724), which when mutated leads to disease.
47	srx-22	F31F4.3	n/a	chrV 680,688	C. elegans SRX-22 protein ;
48	vab-15	R07B1.1	n/a	chrX 9,848,439	The vab-15 gene encodes a msh-like homeobox gene that appears required for production of touch cell precursors, and that is orthologous to the human gene MSH HOMEO BOX HOMOLOG 1 (MSX1; OMIM:142983) which when mutated leads to disease.
49	C01F6.1	C01F6.1	n/a	chrIV 9,098,665	C01F6.1 encodes a putative calcium-dependent phospholipid binding protein of the copine family; C01F6.1 is required for sperm to normally migrate towards a PUFA-based signal exuded by oocytes; C01F6.1(RNAi) hermaphrodites are infertile, both through aberrant loss of their own sperm and through failure of males to effectively inseminate them.
50	srj-10	F14H3.1	n/a	chrV 16,073,333	C. elegans SRJ-10 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)