UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nlp-1	C01C4.1	6e-98	chrX 3,727,992	nlp-1 encodes a predicted neuropeptide-like protein of the MSFamide family with similarity to Aplysia californica (sea hare) buccalin, a neuropeptide that regulates acetylcholine-induced muscle contraction; NLP-1 is expressed in the phasmid PHB tail sensory neuron, lateral neurons, head neurons, and the intestine; the precise role of NLP-1 in nervous system function and development is not yet known.
2	snt-4	T23H2.2	n/a	chrI 6,438,658	C. elegans SNT-4 protein; contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR001565 (Synaptotagmin), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
3	ZC204.1	ZC204.1	n/a	chrII 1,666,906	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
4	flp-7	F49E10.3	n/a	chrX 5,886,304	flp-7 encodes an MVRFamide-containing peptide that, upon injection into A. suum, produces paralysis and loss of locomotory waveforms, increased body length, and decreased cAMP production.
5	F20B6.6	F20B6.6	n/a	chrX 4,201,908	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domain IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
6	flp-19	M79.4	n/a	chrX 10,605,248	C. elegans FLP-19 protein ;
7	nlp-8	D2005.2	n/a	chrI 7,801,131	C. elegans NLP-8 protein ;
8	C47D2.1	C47D2.1	n/a	chrX 8,215,243
9	F21F3.1	F21F3.1	n/a	chrI 4,909,304	contains similarity to Pfam domain PF01436 NHL repeat contains similarity to Interpro domains IPR000720 (Peptidyl-glycine alpha-amidating monooxygenase), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013017 (NHL repeat, subgroup), IPR015943 (WD40/YVTN repeat-like), IPR001258 (NHL repeat)
10	flp-21	C26F1.10	n/a	chrV 7,793,674	flp-21 encodes a single FMRFamide-related neuropeptide (FaRP) that serves as a ligand for NPR-1, a G protein-coupled receptor that regulates social versus solitary feeding behavior in several Caenorhabditis species; genetic analysis suggests that FLP-21 acts through NPR-1 to inhibit social feeding behavior; FLP-21 is expressed in the ADL, ASE and ASH sensory neurons, the URA motor neurons, the MC, M2 and M4 pharyngeal neurons, and the intestine; flp-21 encodes the only FMRFamide-related neuropeptide (FaRP) encoded by the C. elegans genome that activates both the social (215F) and the solitary (215V) forms of NPR-1 in both Xenopus oocytes and pharyngeal assays.
11	nlp-14	D1009.4	n/a	chrX 8,918,369	C. elegans NLP-14 protein; contains similarity to Interpro domain IPR005829 (Sugar transporter, conserved site)
12	xbx-3	M04D8.6	n/a	chrIII 10,036,315	C. elegans XBX-3 protein ;
13	pqn-48	K07D4.8	n/a	chrII 4,040,965	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
14	sbt-1	T03D8.3	n/a	chrV 20,823,688	C. elegans SBT-1 protein; contains similarity to Pfam domain PF05281 Neuroendocrine protein 7B2 precursor (Secretogranin V) contains similarity to Interpro domain IPR007945 (Neuroendocrine 7B2 precursor)
15	nlp-3	F48C11.3	n/a	chrX 13,178,076	nlp-3 encodes a neuropeptide-like protein of the GFxGF family with similarity to orcokinins, highly conserved peptides native to crustaceans that enhance hindgut contractions; NLP-3 is expressed in neurons in the head, pharynx, and vulva, and in the intestine; the precise role of NLP-3 in nervous system function and development is not yet clear.
16	cal-2	C18E9.1	n/a	chrII 8,961,053	cal-2 encodes a calmodulin homolog required for embryonic development or viability; CAL-2 is closely similar to its paralogs CAL-1, CAL-3, CAL-4 and CMD-1.
17	flp-5	C03G5.7	n/a	chrX 8,529,581	flp-5 encodes a predicted FMRFamide-like peptide neurotransmitter that increases action potential frequency in the pharyngeal muscle when applied to the pharynx of dissected worms; expressed in the sensory neurons ASE and PVM.
18	cal-4	T07G12.1	n/a	chrIV 10,528,321	cal-4 encodes one of five predicted C. elegans calcium-binding calmodulin homologs (the others being CAL-1, CAL-2, CAL-3 and CMD-1); as loss of cal-4 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of CAL-4 in C. elegans development and/or behavior is not yet known.
19	C02B8.3	C02B8.3	n/a	chrX 8,139,820
20	F20A1.10	F20A1.10	n/a	chrV 7,052,940
21	C54C6.5	C54C6.5	n/a	chrIII 3,549,652	contains similarity to Mycoplasma pulmonis Hypothetical protein MYPU_4440.; TR:Q98QC2
22	flp-3	W07E11.2	n/a	chrX 10,092,469	flp-3 encodes nine copies of a GTMRFamide-containing peptide that is predicted to function as a neuropeptide that inhibits pharyngeal action potential in a manner similar to octopamine without having a significant effect on basal resting membrane potential; expressed in three pairs of neurons IL1D, OL1, URB.
23	M04D8.7	M04D8.7	n/a	chrIII 10,037,728	contains similarity to Sulfolobus tokodaii Putative cytochrome o ubiquinol oxidase assembly factor.; TR:Q970T4
24	F10F2.4	F10F2.4	n/a	chrIII 4,624,572	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
25	C33G8.4	C33G8.4	n/a	chrV 7,006,530
26	Y37H2C.1	Y37H2C.1	n/a	chrV 18,275,256	contains similarity to Homo sapiens SIDT1 protein; ENSEMBL:ENSP00000377416
27	ttr-23	T21C9.8	n/a	chrV 10,589,462	C. elegans TTR-23 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
28	T21C12.3	T21C12.3	n/a	chrIII 10,538,504	contains similarity to Leptospira interrogans Hypothetical protein.; TR:Q8EZD2
29	F19G12.1	F19G12.1	n/a	chrX 1,431,242	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
30	F14D7.8	F14D7.8	n/a	chrV 14,312,353	contains similarity to Staphylococcus epidermidis Conserved hypothetical protein.; TR:Q8CSE5
31	ZK353.4	ZK353.4	n/a	chrIII 8,388,992	contains similarity to Schizosaccharomyces pombe Uncharacterized serine/threonine-rich protein PB15E9.01c precursor.; SW:Q8TFG9
32	C18G1.1	C18G1.1	n/a	chrV 4,779,553
33	drn-1	C54A12.4	n/a	chrII 5,271,026	C. elegans DRN-1 protein; contains similarity to Pfam domain PF00071 Ras family contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
34	C15B12.4	C15B12.4	n/a	chrX 6,472,014	contains similarity to Interpro domain IPR000158 (Cell division protein FtsZ, N-terminal)
35	zig-5	Y48A6A.1	n/a	chrIII 10,952,247	zig-5 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-5::gfp reporter fusion is expressed in a number of neurons, including PVT, VD1-13, RID, AFD, ASK, RIV, RIB, PVQ, DVA, and RIS; zig-5::gfp is detected in the PVT neuron beginning at the three-fold stage of embryogenesis and continuing throughout larval development; loss of zig-5 activity in large-scale RNAi screens has been reported to result in low levels of embryonic lethality.
36	F58B4.3	F58B4.3	n/a	chrV 10,930,269	contains similarity to Homo sapiens similar to bA88M19.1 (EGF-like-domain multiple 5 protein); ENSEMBL:ENSP00000223618
37	nlp-11	ZK1320.10	n/a	chrII 9,690,787	C. elegans NLP-11 protein ;
38	nlp-37	F48B9.4	n/a	chrX 2,163,570	C. elegans NLP-37 protein ;
39	T23B3.6	T23B3.6	n/a	chrI 6,707,989
40	hen-1	C36B7.7	n/a	chrX 7,116,551	hen-1 encodes a secreted protein that contains a low-density lipoprotein (LDL) receptor motif A; HEN-1 activity is required for integration of sensory stimuli and behavioral plasticity; a hen-1::GFP reporter is expressed in pharyngeal muscles, the vulva, and weakly in a subset of neurons; antibodies to HEN-1 protein detect expression exclusively in the AIY and ASE neurons, where HEN-1 appears to localize to cell bodies and in a punctate pattern in nerve ring axons at sites of synapse formation; HEN-1 expression in AIY appears to be under the control of the TTX-3 LIM domain transcription factor.
41	ins-30	ZC334.2	n/a	chrI 14,035,617	ins-30 encodes an insulin-like peptide.
42	ins-18	T28B8.2	n/a	chrI 8,148,533	ins-18 encodes one of 40 C. elegans insulin/IGF-like peptides; INS-18, along with INS-1, are the only two C. elegans insulins that contain a C peptide, characteristic of mammalian insulins, connecting the B and A chains; overexpression of ins-18 induces dauer arrest at 26 degrees C and enhances the dauer arrest seen in a daf-2 mutant at 20 degrees C, suggesting that INS-18 functions to antagonize DAF-2 receptor signaling; ins-18::gfp reporters are expressed in neurons and the intestine.
43	F58B4.4	F58B4.4	n/a	chrV 10,931,009	contains similarity to Plasmodium yoelii Rhoptry protein.; TR:Q26216
44	F53A9.6	F53A9.6	n/a	chrX 8,713,583	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002395 (HMW kininogen)
45	ida-1	B0244.2	n/a	chrIII 5,760,627	ida-1 encodes a protein tyrosine phosphatase-like receptor, orthologous to the mammalian type I diabetes autoantigens IA-2 and phogrin that are expressed in dense core vesicles of neuroendocrine tissue and involved in regulated protein secretion; in C. elegans, IDA-1 appears to be required for regulating presynaptic neurotransmission and in particular, for the neuropeptidergic control of egg-laying; ida-1 interacts genetically with unc-31 and unc-64, which encode proteins required for dense core vesicle fusion and exocytosis; ida-1 expression is detected in a subset of neurons in the anterior nerve ring, the ventral nerve cord, the tail, and the vulva, including the VC vulval motoneurons and the HSN egg-laying neurons; ida-1 is also detected in the vulval uv1 cells, non-neuronal cells that contain neurosecretory-like vesicles.
46	T02E9.1	T02E9.1	n/a	chrV 11,351,210	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
47	F10E7.9	F10E7.9	n/a	chrII 7,108,173	contains similarity to Pfam domain PF00324 Amino acid permease contains similarity to Interpro domain IPR004841 (Amino acid permease-associated region)
48	R07C12.1	R07C12.1	n/a	chrIV 4,153,281
49	F41D3.8	F41D3.8	n/a	chrI 12,267,803	contains similarity to Pfam domain PF01697 (Domain of unknown function)
50	F41G3.10	F41G3.10	n/a	chrII 6,749,016	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)