UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	bath-24	B0047.3	1.9999999999999998e-134	chrII 2,045,144	C. elegans BATH-24 protein; contains similarity to Pfam domains PF00917 (MATH domain) , PF00651 (BTB/POZ domain) contains similarity to Interpro domains IPR002083 (MATH), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ), IPR000210 (BTB/POZ-like)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	C40C9.3	C40C9.3	n/a	chrX 13,647,897	contains similarity to Conus textile Conotoxin scaffold VI/VII.; TR:Q9U653
4	nas-22	T11F9.6	n/a	chrV 11,475,004	nas-22 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-22::GFP promoter fusion is expressed in the uterus, uterine and vulval muscles, and uterine seam cell.
5	C29F9.12	C29F9.12	n/a	chrIII 121,876
6	K08D9.5	K08D9.5	n/a	chrV 3,225,335	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
7	C49H3.4	C49H3.4	n/a	chrIV 7,915,959	contains similarity to Pfam domain PF01423 LSM domain contains similarity to Interpro domains IPR001163 (Like-Sm ribonucleoprotein, core), IPR006649 (Like-Sm ribonucleoprotein, eukaryotic and archaea-type, core), IPR014761 (UV excision repair protein Rad23, C-terminal), IPR010920 (Like-Sm ribonucleoprotein-related, core)
8	nlp-23	T24D8.4	n/a	chrX 2,342,692	nlp-23 encodes three predicted neuropeptide-like proteins; in C. elegans, nlp-23 is part of the FRPamide neuropeptide family that also contains nlp-2 and nlp-22; nlp-23 is expressed in the tail and in dorsal and ventral hypodermis; as loss of nlp-23 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of the nlp-23-encoded peptides in development and/or behavior is not yet known.
9	fkh-6	B0286.5	n/a	chrII 4,381,579	fkh-6 encodes one of 15 C. elegans forkhead transcription factors; fkh-6 is required for several aspects of male gonadogenesis including asymmetric cell division, cell migration and sex determination and appears to act downstream of tra-1; FKH-6 is specifically expressed in the gonad.
10	C54D10.10	C54D10.10	n/a	chrV 12,449,327	contains similarity to Pfam domains PF00788 (Ras association (RalGDS/AF-6) domain) , PF02204 (Vacuolar sorting protein 9 (VPS9) domain) contains similarity to Interpro domains IPR013995 (Vacuolar sorting protein 9, subgroup), IPR003123 (Vacuolar sorting protein 9), IPR000159 (Ras-association)
11	C09G9.7	C09G9.7	n/a	chrIV 8,878,734	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
12	ceh-60	F22A3.5	n/a	chrX 6,527,181	ceh-60 encodes a homeodomain-containing protein that is a member of the PBX family of homeodomain transcription factors; loss of ceh-60 activity via large-scale RNAi results in reduced fat content, sterility, and variable embryonic lethality.
13	F53F4.12	F53F4.12	n/a	chrV 13,626,710	contains similarity to Plasmodium falciparum Histidine-rich protein.; SW:HRP3_PLAFS
14	dop-4	C52B11.3	n/a	chrX 1,296,964	C. elegans DOP-4 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000929 (Dopamine receptor), IPR002233 (Adrenergic receptor), IPR001671 (Melanocortin/ACTH receptor), IPR000995 (Muscarinic acetylcholine receptor), IPR000276 (GPCR, rhodopsin-like)
15	fbxa-98	C08F11.5	n/a	chrIV 13,634,329	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
16	C44B12.6	C44B12.6	n/a	chrIV 1,131,250	contains similarity to Interpro domain IPR010345 (Interleukin-17)
17	F57B1.5	F57B1.5	n/a	chrV 13,208,243	contains similarity to unidentified bacterium Hypothetical protein.; TR:Q93DU5
18	R11A8.2	R11A8.2	n/a	chrIV 10,359,115	contains similarity to Interpro domains IPR008991 (Translation protein SH3-like), IPR005824 (KOW), IPR000467 (D111/G-patch)
19	T26E4.10	T26E4.10	n/a	chrV 15,798,017	contains similarity to Rattus norvegicus Voltage-dependent T-type calcium channel alpha-1I subunit (CaVT.3).; SW:CCAI_RAT
20	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
21	C50H11.1	C50H11.1	n/a	chrV 3,090,166	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
22	fbxa-56	T12B5.7	n/a	chrIII 937,668	C. elegans FBXA-56 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
23	F22E12.3	F22E12.3	n/a	chrV 10,461,278	contains similarity to Petroselinum crispum Reverse transcriptase (Fragment).; TR:Q9ZRL1
24	F49C12.3	F49C12.3	n/a	chrIV 9,301,257	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
25	F36G9.3	F36G9.3	n/a	chrV 15,958,350	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF05978 (Eukaryotic protein of unknown function (DUF895)) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
26	ZK742.2	ZK742.2	n/a	chrV 7,802,661	contains similarity to Homo sapiens Isoform 1 of Uncharacterized protein KIAA1530; ENSEMBL:ENSP00000374501
27	ulp-5	K02F2.4	n/a	chrI 6,813,375	C. elegans ULP-5 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)
28	ccdc-55	C16C10.6	n/a	chrIII 4,167,827	C. elegans CCDC-55 protein ; contains similarity to Mus musculus Coiled-coil domain-containing protein 55.; SW:Q5NCR9
29	C42C1.9	C42C1.9	n/a	chrIV 12,290,184	contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
30	uev-3	F26H9.7	n/a	chrI 9,311,457	uev-3 encodes a ubiquitin-conjugating enzyme (UBC or E2) variant that contains the UBC motif, but lacks the critical active-site cysteine residue necessary for catalytic activity; as loss of UEV-3 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UEV-3 in C. elegans development and/or behavior is not yet known; based on similarity to Saccharomyces cerevisiae and human proteins, however, UEV-3 may play a role in cell cycle control or response to stress or DNA damage.
31	F25H9.7	F25H9.7	n/a	chrV 13,468,733	contains similarity to Pfam domain PF05882 ACN9 family contains similarity to Interpro domain IPR008381 (ACN9)
32	F48E8.3	F48E8.3	n/a	chrIII 5,462,687	contains similarity to Pfam domains PF00890 (FAD binding domain) , PF01266 (FAD dependent oxidoreductase) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR010960 (Flavocytochrome c), IPR006076 (FAD dependent oxidoreductase), IPR003953 (Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal), IPR016040 (NAD(P)-binding)
33	F31A9.2	F31A9.2	n/a	chrX 1,795,240
34	C54F6.12	C54F6.12	n/a	chrV 7,537,395
35	H25K10.6	H25K10.6	n/a	chrIV 16,235,400	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
36	F48E8.2	F48E8.2	n/a	chrIII 5,466,142	contains similarity to Mus musculus E2F-associated phosphoprotein (EAPP).; SW:Q5BU09
37	dhs-11	Y39A1A.11	n/a	chrIII 10,641,861	dhs-11 encodes a short-chain dehydrogenase predicted to be mitochondrial.
38	W05H7.2	W05H7.2	n/a	chrX 1,435,503
39	lin-11	ZC247.3	n/a	chrI 10,251,797	lin-11 encodes a predicted LIM homeodomain transcription factor that affects vulval development, neuronal development and fate specification, utse cell differentiation, and fertility; it is expressed in some neurons, the vulva, pi cells and their progeny, and the spermatheca.
40	srd-16	C04E6.9	n/a	chrV 5,899,272	C. elegans SRD-16 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
41	mls-1	H14A12.4	n/a	chrIII 7,461,052	mls-1 encodes a T-box transcription factor orthologous to members of the Tbx1 subfamily of T-box transcription factors (OMIM:602054, mutations in human TBX1 are associated with the developmental disorder DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS)); MLS-1 is required for fate specification of the eight nonstriated uterine muscle cells generated during postembryonic development, and ectopic expression of MLS-1 is sufficient for uterine muscle specification in other mesodermal lineages; mls-1 reporter gene expression is detected in uterine progenitors and differentiated uterine muscles, Type 2 vulval muscles, the left and right intestinal muscles, and the anal depressor muscle; mls-1 expression is positively regulated by the basic helix-loop-helix transcription factors HLH-8/Twist and HLH-2/Daughterless.
42	K10H10.5	K10H10.5	n/a	chrII 14,502,114	contains similarity to Interpro domain IPR001030 (Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)
43	R09H3.1	R09H3.1	n/a	chrX 1,660,650	contains similarity to Sulfolobus solfataricus DNA double-strand break repair rad50 ATPase.; SW:Q97WH0
44	str-136	F21F8.9	n/a	chrV 8,278,202	C. elegans STR-136 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1)
45	C10G8.3	C10G8.3	n/a	chrV 5,313,573	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domain IPR002223 (Proteinase inhibitor I2, Kunitz metazoa)
46	clec-235	F36D3.10	n/a	chrV 16,531,589	C. elegans CLEC-235 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
47	F08B6.1	F08B6.1	n/a	chrI 6,760,893	contains similarity to Interpro domain IPR010916 (TonB box, conserved site)
48	mom-4	F52F12.3	n/a	chrI 9,898,245	mom-4 encodes a MAP kinase kinase kinase-related protein orthologous to Drosophila Tak1 and the vertebrate MAPKKK7 proteins; during embryonic development, mom-4 activity is required for positive regulation of the Wnt pathway signaling that governs anterior/posterior (A/P) polarity: MOM-4 stimulates the WRM-1/LIT-1-dependent phosphorylation of POP-1, a TCF/LEF-related transcription factor, leading to its downregulation in posterior daughters of A/P cell divisions.
49	F47B10.6	F47B10.6	n/a	chrX 10,888,627
50	his-1	T10C6.14	n/a	chrV 16,042,648	his-1 encodes an H4 histone; his-1 is contained within the histone gene cluster HIS1; transcript analysis suggests that it encodes the major class of H4 transcripts.