UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T09E11.1	T09E11.1	0	chrI 12,338,593	contains similarity to Pfam domain PF03360 Glycosyltransferase family 43 contains similarity to Interpro domain IPR005027 (Glycosyl transferase, family 43)
2	C52B11.5	C52B11.5	n/a	chrX 1,274,112	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
3	W06B4.3	W06B4.3	n/a	chrII 4,464,653	contains similarity to Pfam domain PF05131 Pep3/Vps18/deep orange family contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR007810 (Pep3/Vps18/deep orange), IPR016024 (Armadillo-type fold)
4	srd-2	R05H5.1	n/a	chrII 10,186,817	C. elegans SRD-2 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
5	W06D11.4	W06D11.4	n/a	chrX 12,302,364	contains similarity to Pfam domain PF08123 Histone methylation protein DOT1 contains similarity to Interpro domain IPR013110 (Histone methylation DOT1)
6	C06A5.4	C06A5.4	n/a	chrI 5,981,191	contains similarity to Interpro domain IPR006578 (MADF)
7	rheb-1	F54C8.5	n/a	chrIII 9,455,024	rheb-1 encodes a GTPase orthologous to the mammalian Rheb and Rheb1 GTPases; loss of rheb-1 activity via RNAi indicates that RHEB-1 is involved in the mitochondrial unfolded protein response and that its function is required for normal growth rates, body size, osmoregulation, reproduction, and locomotion.
8	lin-24	B0001.1	n/a	chrIV 12,132,269	lin-24 was identified in screens for mutations that result in altered vulval cell lineages; lin-24 is defined by two alleles, the first of which, a partially dominant mutation, generally results in vulvaless animals, while the second, a non-null amber mutation that is also partially dominant, results in wild-type animals when homozygous, but vulvaless animals when heterozygous with a wild-type allele; morphological examination of lin-24 animals indicates that some of the Pn.p cells that normally make up the vulva undergo inappropriate cell death that is dependent upon the ced-2, ced-5, and ced-10 engulfment genes, but not on the ced-3 and ced-4 killing genes; the precise molecular identity of lin-24 has not yet been reported.
9	sra-31	C56C10.5	n/a	chrII 6,577,792	C. elegans SRA-31 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
10	nhr-264	F14A5.1	n/a	chrIV 9,293,087	C. elegans NHR-264 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
11	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
12	B0432.9	B0432.9	n/a	chrII 283,160	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)
13	K11E4.2	K11E4.2	n/a	chrX 13,718,299	contains similarity to Pfam domain PF00017 SH2 domain contains similarity to Interpro domains IPR006020 (Phosphotyrosine interaction region), IPR000980 (SH2 motif)
14	F58B3.6	F58B3.6	n/a	chrIV 11,637,391	contains similarity to Pfam domains PF04836 (Interferon-related protein conserved region) , PF05004 (Interferon-related developmental regulator (IFRD)) contains similarity to Interpro domains IPR007701 (Interferon-related developmental regulator), IPR006921 (Interferon-related protein conserved region), IPR016024 (Armadillo-type fold)
15	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
16	ulp-4	C41C4.6	n/a	chrII 8,132,271	C. elegans ULP-4 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)
17	srt-70	B0238.6	n/a	chrV 5,258,776	C. elegans SRT-70 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
18	F28C10.3	F28C10.3	n/a	chrX 533,819	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
19	his-12	ZK131.6	n/a	chrII 13,821,298	his-12 encodes an H2A histone; his-12 is contained within the histone gene cluster HIS3.
20	math-37	R52.9	n/a	chrII 2,121,460	C. elegans MATH-37 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
21	C26D10.3	C26D10.3	n/a	chrII 8,327,460	contains similarity to Pfam domain PF07992 Pyridine nucleotide-disulphide oxidoreductase contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000759 (Adrenodoxin reductase), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
22	sru-29	C50C10.2	n/a	chrV 9,812,012	C. elegans SRU-29 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
23	C41D11.4	C41D11.4	n/a	chrI 4,442,876
24	T27E9.6	T27E9.6	n/a	chrIII 13,475,636	contains similarity to Bradyrhizobium japonicum Bsl1006 protein.; TR:Q89VN9
25	C10C6.6	C10C6.6	n/a	chrIV 11,476,280	contains similarity to Pfam domains PF00122 (E1-E2 ATPase) , PF00702 (haloacid dehalogenase-like hydrolase) contains similarity to Interpro domains IPR008250 (E1-E2 ATPase-associated region), IPR006069 (ATPase, P-type cation exchange, alpha subunit), IPR006544 (P-type ATPase of unknown pump specificity (type V)), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR005834 (Haloacid dehalogenase-like hydrolase)
26	emb-27	F10B5.6	n/a	chrII 8,160,979	emb-27 encodes a tetratricopeptide repeat (TPR)-containing protein that is the C. elegans ortholog of the anaphase-promoting complex (APC) subunit APC-6 (CDC16); required maternally and paternally, EMB-27 activity is essential for proper execution of the metaphase-to-anaphase transition during meiosis (both oogenesis and spermatogenesis) and mitosis (during germline proliferation); EMB-27 activity is also critical for embryonic anterior-posterior (A-P) axis formation, production of the secreted eggshell, and normal vulval development; in establishing the embryonic A-P axis, EMB-27 likely acts upstream of the separin protease to ensure proper localization of PAR-3 and PAR-2 to the anterior and posterior cortices, respectively.
27	nhr-168	C50B6.8	n/a	chrV 13,332,476	C. elegans NHR-168 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
28	polq-1	W03A3.2	n/a	chrIII 5,797,057	C. elegans POLQ-1 protein; contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00476 (DNA polymerase family A) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR001098 (DNA-directed DNA polymerase, family A), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR002298 (DNA polymerase A), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
29	F09F7.3	F09F7.3	n/a	chrIII 5,560,978	contains similarity to Pfam domains PF04566 (RNA polymerase Rpb2, domain 4) , PF04561 (RNA polymerase Rpb2, domain 2) , PF04567 (RNA polymerase Rpb2, domain 5) , PF04565 (RNA polymerase Rpb2, domain 3) , PF00562 (RNA polymerase Rpb2, domain 6) , PF04560 (RNA polymerase Rpb2, domain 7) , PF04563 (RNA polymerase beta subunit) contains similarity to Interpro domains IPR007120 (DNA-directed RNA polymerase, subunit 2, domain 6), IPR007641 (RNA polymerase Rpb2, domain 7), IPR007644 (RNA polymerase, beta subunit, protrusion), IPR015712 (DNA-directed RNA polymerase, subunit 2), IPR007645 (RNA polymerase Rpb2, domain 3), IPR007642 (RNA polymerase Rpb2, domain 2), IPR014724 (RNA polymerase Rpb2, OB-fold), IPR007646 (RNA polymerase Rpb2, domain 4), IPR007647 (RNA polymerase Rpb2, domain 5), IPR007121 (RNA polymerase, beta subunit, conserved site)
30	itsn-1	Y116A8C.36	n/a	chrIV 17,122,917	tag-11/Y116A8C.36 encodes a homolog of human NCF1, which when mutated leads to chronic granulomatous disease (OMIM:306400).
31	srh-239	T26H5.3	n/a	chrV 15,446,542	C. elegans SRH-239 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	C25F6.6	C25F6.6	n/a	chrX 5,450,509
33	Y48A5A.1	Y48A5A.1	n/a	chrIV 1,967,552	contains similarity to Pfam domain PF04925 SHQ1 protein contains similarity to Interpro domain IPR007009 (SHQ1 protein)
34	dat-1	T23G5.5	n/a	chrIII 9,244,759	dat-1 encodes a plasma membrane dopamine transporter; DAT-1 is predicted to regulate dopaminergic neurotransmission via reuptake of dopamine into presynaptic neurons; when expressed in HeLa cells, DAT-1 exhibits high affinity, saturable dopamine transport; further, in primary cultures of C. elegans dopaminergic neurons, DAT-1 also exhibits a channel mode of conduction that leads to membrane depolarization; in hermaphrodites, dat-1 is expressed in the eight dopaminergic neurons (4 CEPs, 2 ADEs, and 2 PDEs), while in males dat-1 is additionally expressed in the three pairs of tail dopaminergic neurons; dat-1 expression begins during embryogenesis with the exception of expression in the PDE neurons which are born postembryonically.
35	str-40	C50H11.12	n/a	chrV 3,068,667	C. elegans STR-40 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	B0302.5	B0302.5	n/a	chrX 17,194,125
37	srw-118	C44C3.5	n/a	chrV 2,979,418	C. elegans SRW-118 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
38	C01H6.9	C01H6.9	n/a	chrI 7,231,276	C01H6.9 encodes a homolog of haploid germ cell-specific nuclear protein kinase (haspin) that specifically binds GOA-1 in yeast two-hybrid assays; C01H6.9 is expressed in PHB sensory neurons and PVT interneurons in the tail, several unidentified neurons in the head (with projections to the nose and nerve ring), and intestinal cells, with mainly nuclear localization; C01H6.9 has no obvious function or phenotype in RNAi assays, either alone or with inactivation of a close paralog (F22H10.5).
39	srgp-1	F12F6.5	n/a	chrIV 11,574,575	C. elegans SRGP-1 protein; contains similarity to Pfam domains PF00620 (RhoGAP domain) , PF00611 (Fes/CIP4 homology domain) contains similarity to Interpro domains IPR001060 (Cdc15/Fes/CIP4), IPR008936 (Rho GTPase activation protein), IPR000198 (RhoGAP)
40	F13H8.3	F13H8.3	n/a	chrII 6,264,731	contains similarity to Pfam domain PF01156 Inosine-uridine preferring nucleoside hydrolase contains similarity to Interpro domain IPR001910 (Inosine/uridine-preferring nucleoside hydrolase)
41	str-193	C50C10.6	n/a	chrV 9,821,161	C. elegans STR-193 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	F52E10.3	F52E10.3	n/a	chrX 16,283,853	contains similarity to Salmonella typhimurium Secretion system apparatus protein ssaM.; SW:SSAM_SALTY
43	EEED8.6	EEED8.6	n/a	chrII 5,385,733	EEED8.6 encodes an ATP/ADP-activated metallocarboxypeptidase, orthologous to mammalian AGBL4 proteins, that may function in vivo as an alpha-tubulin C-terminal tyrosine carboxypeptidase; recombinant EEED8.6 is active in vitro on several different C-terminal amino acids of synthetic peptide substrates (with carboxypeptidase A- and B-like, but not O-like specificity); unlike most carboxypeptidases, but like tubulin carboxypeptidase, EEED8.6 is inhibited by high salt or by Z-Glu-Tyr dipeptide; EEED8.6 and its mammalian AGBL4 orthologs, along with other proteins such as mammalian AGBL5, comprise a M14D2 peptidase subfamily; by homolog-based structural modelling, EEED8.6 is predicted to have an unusually open active site.
44	C40H5.2	C40H5.2	n/a	chrX 11,754,976	contains similarity to Bifidobacterium longum Possible magnesium and cobalt transport protein.; TR:Q8G4E0
45	hda-2	C08B11.2	n/a	chrII 8,021,602	hda-2 encodes a Class I histone deacetylase; by homology, HDA-2 is predicted to function in deacetylation of histone residues and transcriptional regulation; loss of hda-2 activity via RNAi results in an increased spontaneous mutation rate, suggesting that hda-2 also plays a role in regulating genome stability.
46	C25G6.5	C25G6.5	n/a	chrX 1,253,316	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002232 (5-Hydroxytryptamine 6 receptor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
47	srbc-17	C45H4.3	n/a	chrV 2,178,415	C. elegans SRBC-17 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
48	C24H12.2	C24H12.2	n/a	chrII 437,796
49	F41G4.5	F41G4.5	n/a	chrX 16,831,782
50	spp-19	K04A8.9	n/a	chrV 6,559,648	C. elegans SPP-19 protein; contains similarity to Interpro domains IPR011001 (Saposin-like), IPR008139 (Saposin B)