UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F41E7.7	F41E7.7	5e-20	chrX 10,311,728	contains similarity to Drosophila grimshawi Chorion protein S18.; SW:CH18_DROGR
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	unc-46	C04F5.3	n/a	chrV 5,098,120	unc-46 encodes a novel protein with a single predicted transmembrane domain; UNC-46 and UNC-47, a novel transmembrane vesicular GABA transporter, are required in GABAergic neurons for all GABA neurotransmission, specifically for loading of GABA into synaptic vesicles, where UNC-46 is localized; UNC-46 localization requires UNC-47, which when overexpressed can rescue unc-46 mutant animals.
4	K12H6.10	K12H6.10	n/a	chrII 2,822,965
5	str-47	F07C4.1	n/a	chrV 7,646,392	C. elegans STR-47 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
6	C49C3.15	C49C3.15	n/a	chrIV 17,334,573	contains similarity to Interpro domain IPR002101 (Myristoylated alanine-rich C-kinase substrate MARCKS)
7	sre-54	C50E10.6	n/a	chrII 12,333,899	C. elegans SRE-54 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
8	C49F5.5	C49F5.5	n/a	chrX 11,986,477	contains similarity to Pfam domain PF02135 TAZ zinc finger contains similarity to Interpro domain IPR000197 (Zinc finger, TAZ-type)
9	Y54E5A.2	Y54E5A.2	n/a	chrI 14,694,856	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
10	Y57A10B.2	Y57A10B.2	n/a	chrII 12,376,431	contains similarity to Homo sapiens RNA binding protein; ENSEMBL:ENSP00000301740
11	fip-3	C06E1.5	n/a	chrIII 8,589,320	C. elegans FIP-3 protein ;
12	nhr-158	C17E7.6	n/a	chrV 3,872,180	C. elegans NHR-158 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
13	ptr-19	Y39A1B.2	n/a	chrIII 10,786,410	ptr-19 encodes an ortholog of Drosophila and human PTCHD3, which defines one of seven paralogous families of sterol sensing domain (SSD) proteins; PTR-19 is required for normal development in mass RNAi assays; PTR-19 is expressed in pharynx, hypodermis, nervous system (including head neurons), and other cells.
14	clec-3	C41H7.7	n/a	chrII 3,018,651	C. elegans CLEC-3 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
15	nhr-266	F56H1.2	n/a	chrI 5,738,931	C. elegans NHR-266 protein; contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR003125 (Protein of unknown function WSN)
16	pha-2	M6.3	n/a	chrX 635,373	pha-2 encodes a homeodomain protein that is orthologous to vertebrate Hex proteins required for the development of B lymphocytes and organs derived from foregut endoderm; in C. elegans, pha-2 is essential for proper development and morphogenesis of the pm5 pharyngeal muscles cells during late stages of embryogenesis; in regulating pm5 fate specification, PHA-2 appears to act downstream of the organ identity factor PHA-4, and upstream of ceh-22, whose expression it may negatively regulate in pm5; a rescuing PHA-2::GFP reporter is expressed in pharyngeal cells, intestinal-rectal cells, and postembryonic head neurons.
17	ceh-17	D1007.1	n/a	chrI 4,569,495	ceh-17 encodes a phox-2-like homeodomain protein that is a member of the Q50 paired-like class of homeobox proteins and the vertebrate orthologue of Phox2a and Phox2b; that affects ALA and SIA axonal development; ceh-17 affects ALA and SIA antero-posterior axonal growth and navigation, and is expressed in five neurons of the ring ganglia (ALA and the 4 SIAs) with strongest expression in embryos and in L1 stage larvae.
18	srh-300	Y94A7B.6	n/a	chrV 17,822,964	C. elegans SRH-300 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	acr-15	F25G6.4	n/a	chrV 8,554,009	A homolog of an alpha type nicotinic acetylcholine receptor subunit involved in the mediation of fast synaptic transmission at neuromuscular junctions.
20	F59C6.8	F59C6.8	n/a	chrI 10,511,155	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
21	F42C5.10	F42C5.10	n/a	chrIV 7,323,684	contains similarity to Interpro domains IPR015425 (Actin-binding FH2), IPR000694 (Proline-rich region)
22	F40E12.2	F40E12.2	n/a	chrII 3,612,874	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00023 (Ankyrin repeat) , PF00533 (BRCA1 C Terminus (BRCT) domain) contains similarity to Interpro domains IPR002110 (Ankyrin), IPR003125 (Protein of unknown function WSN), IPR001357 (BRCT)
23	ZC374.2	ZC374.2	n/a	chrX 10,041,531	contains similarity to Pfam domain PF00041 Fibronectin type III domain contains similarity to Interpro domains IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III)
24	math-32	F59H6.4	n/a	chrII 2,012,019	C. elegans MATH-32 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
25	C17G1.5	C17G1.5	n/a	chrX 9,943,135	contains similarity to Hepatitis C virus Non-structural protein 5b (Genome polyprotein) (Fragment).; TR:Q8V1C2
26	F56F11.1	F56F11.1	n/a	chrIII 2,892,177
27	K03B4.4	K03B4.4	n/a	chrV 4,684,430	contains similarity to Interpro domain IPR002411 (Cereal allergen/alpha-amylase inhibitor, rice-type)
28	R09B5.11	R09B5.11	n/a	chrV 1,440,531	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
29	ncr-2	F09G8.4	n/a	chrIII 8,261,990	ncr-2 encodes a homolog of human NPC1, which when mutated leads to Niemann-Pick disease, type C (OMIM:257220).
30	Y37A1B.6	Y37A1B.6	n/a	chrIV 14,038,988	contains similarity to Bacillus amyloliquefaciens Beta-glucanase (BglA) (Fragment).; TR:Q44651
31	adt-1	C02B4.1	n/a	chrX 12,683,974	The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis.
32	ZK1073.2	ZK1073.2	n/a	chrX 16,113,615	contains similarity to Aquifex aeolicus Hypothetical protein AQ_293.; SW:Y293_AQUAE
33	B0554.3	B0554.3	n/a	chrV 434,275
34	F42G2.5	F42G2.5	n/a	chrII 2,417,192	contains similarity to Pfam domains PF00635 (MSP (Major sperm protein) domain) , PF00097 (Zinc finger, C3HC4 type (RING finger)) contains similarity to Interpro domains IPR008962 (PapD-like), IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000535 (Major sperm protein)
35	R102.3	R102.3	n/a	chrIV 10,691,049	contains similarity to Broad bean wilt virus 2 210kDa protein.; TR:Q9E933
36	Y32B12A.1	Y32B12A.1	n/a	chrV 16,488,780	contains similarity to Pfam domain PF00569 Zinc finger, ZZ type contains similarity to Interpro domain IPR000433 (Zinc finger, ZZ-type)
37	C45G3.4	C45G3.4	n/a	chrI 9,219,134	contains similarity to Dictyostelium discoideum Prespore-specific protein (Fragment).; TR:O97140
38	flp-32	R03A10.2	n/a	chrX 15,434,497	C. elegans FLP-32 protein ;
39	R04E5.7	R04E5.7	n/a	chrX 8,797,318
40	mab-5	C08C3.3	n/a	chrIII 7,780,108	mab-5 encodes a homeodomain transcription factor related to the Antennapedia, Ultrabithorax, and abdominal-A family of homeodomain proteins; during postembryonic development, mab-5 is required cell autonomously for specification of posterior cell fates, including hypodermal and neuronal fates, programmed cell deaths, cell proliferation and migration, and fate specification of the male-specific copulatory muscles and sensory rays; in addition, ectopic expression of mab-5 is sufficient to alter cell fates, such as direction of migration or sensory ray identity; in regions of the body where mab-5 expression overlaps with that of lin-39, another C. elegans HOM-C gene, the two genes appear to either compensate for one another's activity or act combinatorially to promote cell fates distinct from those where either gene is expressed alone; a mab-5:lacZ reporter fusion is expressed in cells in the posterior body region from the mid-gastrulation stage of embryogenesis through larval and adult stages; further, antibody staining reveals that MAB-5 expression in the V5 lineage is dynamic, switching on and off several times, while expression in V6 is continuous throughout most of the L1-L3 larval stages; early MAB-5 expression is V6 is dependent upon wild-type activity of pal-1, which encodes the C. elegans Caudal ortholog.
41	str-115	F07B10.3	n/a	chrV 11,269,735	C. elegans STR-115 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	T09E8.4	T09E8.4	n/a	chrV 13,182,889	contains similarity to Pfam domain PF02460 Patched family contains similarity to Interpro domains IPR003392 (Patched), IPR000731 (Sterol-sensing 5TM box)
43	T02H6.5	T02H6.5	n/a	chrII 687,130	contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
44	C17B7.8	C17B7.8	n/a	chrV 3,322,428	C17B7.8 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; C17B7.8 has no clear orthologs in other organisms.
45	Y47D3B.3	Y47D3B.3	n/a	chrIII 11,400,137	contains similarity to Homo sapiens Low-density lipoprotein receptor-related protein 2 precursor; ENSEMBL:ENSP00000263816
46	frm-3	H05G16.1	n/a	chrX 11,578,915	frm-3 encodes a protein containing a FERM domain (Band 4.1 family); expressed in a few cells in the head.
47	nhr-90	ZK488.2	n/a	chrV 611,490	C. elegans NHR-90 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
48	str-87	F59E11.16	n/a	chrV 8,987,304	C. elegans STR-87 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
49	F53B1.3	F53B1.3	n/a	chrX 2,106,394
50	grl-8	ZC487.5	n/a	chrV 6,732,495	grl-8 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.