UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nas-39	F38E9.2	0	chrX 16,464,603	C. elegans NAS-39 protein; contains similarity to Pfam domains PF00008 (EGF-like domain) (2), PF07645 (Calcium binding EGF domain) (2), PF00431 (CUB domain) (4), PF01400 (Astacin (Peptidase family M12A)) contains similarity to Interpro domains IPR015446 (Bone morphogenetic protein 1/tolloid-like protein), IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR001506 (Peptidase M12A, astacin), IPR006210 (EGF), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR013091 (EGF calcium-binding)
2	F16G10.13	F16G10.13	n/a	chrII 2,395,441	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
3	srw-4	F37B4.8	n/a	chrV 2,887,985	C. elegans SRW-4 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
4	F55D12.1	F55D12.1	n/a	chrI 7,884,957	contains similarity to Brachydanio rerio Hypothetical protein.; TR:Q803L4
5	mab-5	C08C3.3	n/a	chrIII 7,780,108	mab-5 encodes a homeodomain transcription factor related to the Antennapedia, Ultrabithorax, and abdominal-A family of homeodomain proteins; during postembryonic development, mab-5 is required cell autonomously for specification of posterior cell fates, including hypodermal and neuronal fates, programmed cell deaths, cell proliferation and migration, and fate specification of the male-specific copulatory muscles and sensory rays; in addition, ectopic expression of mab-5 is sufficient to alter cell fates, such as direction of migration or sensory ray identity; in regions of the body where mab-5 expression overlaps with that of lin-39, another C. elegans HOM-C gene, the two genes appear to either compensate for one another's activity or act combinatorially to promote cell fates distinct from those where either gene is expressed alone; a mab-5:lacZ reporter fusion is expressed in cells in the posterior body region from the mid-gastrulation stage of embryogenesis through larval and adult stages; further, antibody staining reveals that MAB-5 expression in the V5 lineage is dynamic, switching on and off several times, while expression in V6 is continuous throughout most of the L1-L3 larval stages; early MAB-5 expression is V6 is dependent upon wild-type activity of pal-1, which encodes the C. elegans Caudal ortholog.
6	clec-114	C49A1.9	n/a	chrI 14,233,796	C. elegans CLEC-114 protein; contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold)
7	F31A9.1	F31A9.1	n/a	chrX 1,797,616
8	srv-4	F15E6.7	n/a	chrIV 4,286,920	C. elegans SRV-4 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
9	bbs-9	C48B6.8	n/a	chrI 6,920,270	C. elegans BBS-9 protein ; contains similarity to Homo sapiens 95 kDa protein; ENSEMBL:ENSP00000346214
10	F14H8.4	F14H8.4	n/a	chrV 15,024,402	contains similarity to Clostridium acetobutylicum Protein containing a domain related to multimeric flavodoxin WrbAsfamily.; TR:Q97H25
11	C38C5.1	C38C5.1	n/a	chrX 5,560,137
12	lgc-1	T05B4.1	n/a	chrV 4,136,911	C. elegans LGC-1 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR002394 (Nicotinic acetylcholine receptor, N-terminal), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
13	C24A8.1	C24A8.1	n/a	chrX 4,323,582	C24A8.1 encodes an homolog of mammalian D2 or D3 dopamine receptors, and a paralog of DOP-2/-3; C24A8.1 is expressed in the nervous system; because of its paralogy, C24A8.1 might act redundantly with DOP-2 to promote the basal slowing response to bacterial feeding, or it might account for the residual response to excess dopamine seen in triple dop-1/-2/-3 mutants; but C24A8.1 otherwise has no obvious function in RNAi assays of brood size, egg laying, pharyngeal pumping, locomotion, or male mating.
14	nhr-190	F48G7.11	n/a	chrV 641,845	C. elegans NHR-190 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
15	str-150	T03E6.4	n/a	chrV 16,584,195	C. elegans STR-150 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
16	acr-12	R01E6.4	n/a	chrX 13,534,608	acr-12 encodes a nicotinic acetylcholine receptor (nAChR) alpha subunit that is a member of the ACR-8-like group of C. elegans nAChR subunits; as an nAChR subunit, ACR-12 is predicted to mediate fast excitatory neurotransmission, however loss of acr-12 activity via mutation or RNAi results in no obvious defects; ACR-12 copurifies with UNC-29 and LEV-1, suggesting that ACR-12 can form receptors with these two non-alpha AChR subunits; an ACR-12::GFP fusion protein is expressed exclusively in ventral cord motor neurons, including the D neurons; in vivo, ACR-12 colocalizes with some, but not all, UNC-38-containing postsynaptic receptor clusters, suggesting that ACR-12 contributes to only a subset of these receptor clusters.
17	srx-136	F09F3.12	n/a	chrV 13,858,174	C. elegans SRX-136 protein ;
18	T25E4.2	T25E4.2	n/a	chrII 5,581,240
19	sra-1	AH6.4	n/a	chrII 9,520,857	sra-1 encodes a predicted seven transmembrane receptor; expressed in the male SPD and SPV neurons.
20	F38B6.7	F38B6.7	n/a	chrX 6,697,033	contains similarity to Interpro domain IPR006150 (Cysteine-rich repeat)
21	F49D11.2	F49D11.2	n/a	chrI 10,922,443	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
22	C08H9.11	C08H9.11	n/a	chrII 9,858,792	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
23	F58E2.2	F58E2.2	n/a	chrIV 3,470,373
24	K10C9.1	K10C9.1	n/a	chrV 1,077,400
25	C17A2.3	C17A2.3	n/a	chrII 3,844,552	contains similarity to Drosophila melanogaster Flybase gene name is CG2975-PA;; FLYBASE:CG2975
26	T05C12.8	T05C12.8	n/a	chrII 8,189,001	contains similarity to Interpro domain IPR002110 (Ankyrin)
27	F21A10.4	F21A10.4	n/a	chrX 10,185,057	contains similarity to Mus musculus Tumor rejection antigen P815A.; SW:TUR8_MOUSE
28	F28F9.3	F28F9.3	n/a	chrIV 3,831,378
29	F45E12.6	F45E12.6	n/a	chrII 7,313,979
30	sto-6	Y71H9A.2	n/a	chrX 11,634,381	C. elegans STO-6 protein; contains similarity to Pfam domain PF01145 SPFH domain / Band 7 family contains similarity to Interpro domains IPR001107 (Band 7 protein), IPR001972 (Stomatin)
31	F16G10.8	F16G10.8	n/a	chrII 2,382,692	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
32	clec-22	F49A5.3	n/a	chrV 16,859,205	C. elegans CLEC-22 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
33	B0207.2	B0207.2	n/a	chrI 5,955,959
34	F38C2.4	F38C2.4	n/a	chrIV 16,270,980	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
35	rac-2	K03D3.10	n/a	chrIV 16,308,987	rac-2 encodes a small Rho family GTPase that, along with CED-10 and MIG-2, is one of three C. elegans Rac-related proteins; genetic studies indicate that rac-2 functions redundantly with mig-2 and ced-10 to regulate CAN and PDE axon pathfinding and CAN cell migration; in addition, rac-2 functions slightly redundant with mig-2 during distal tip cell movement and slightly redundant with ced-10 during cell-corpse phagocytosis; as unc-73 mutations enhance rac-2 defects in axon pathfinding and CAN cell migration, UNC-73/Trio is a likely candidate to act upstream of RAC-2 and positively regulate its GTPase activity in vivo; further, as UNC-115 activity is required to mediate the morphogenetic effects of constitutively active RAC-2(G12V), UNC-115, an actin-binding protein, is likely to be a downstream effector of RAC-2; GFP::RAC-2 reporters expressed in neurons and neuroblasts reveal localization at cell margins and the nerve ring, the latter suggesting that GFP::RAC-2 associates with the axonal plasma membrane.
36	sdz-35	ZC239.12	n/a	chrII 3,208,304	C. elegans SDZ-35 protein; contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
37	str-87	F59E11.16	n/a	chrV 8,987,304	C. elegans STR-87 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	ZK938.6	ZK938.6	n/a	chrII 9,844,266	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
39	F15A8.1	F15A8.1	n/a	chrX 4,441,526
40	srj-5	F31F4.16	n/a	chrV 652,439	C. elegans SRJ-5 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	srw-47	K10G4.2	n/a	chrV 17,261,345	C. elegans SRW-47 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR000276 (GPCR, rhodopsin-like)
42	M05B5.6	M05B5.6	n/a	chrI 7,184,379	contains similarity to Homo sapiens Transient receptor potential cation channel subfamily A member 1; ENSEMBL:ENSP00000262209
43	glr-3	K10D3.1	n/a	chrI 7,119,675	glr-3 encodes a protein that contains a ligand-gated ion channel domain and a receptor family ligand binding domain with similarity to kainate-selective ionotropic glutamate receptor 2 (human GRIK2); expressed in the RIA neuron.
44	ham-1	F53B2.6	n/a	chrIV 12,543,852	ham-1 encodes a novel protein with a winged helix DNA-binding motif; ham-1 is required for the asymmetric divisions of several neuroblasts in the developing embryo and may influence their spindle position; ham-1 mutations also exhibit HSN motor neuron migration defects; HAM-1 interacts with itself in a yeast two-hybrid screen and observations suggest that its multimerization is required for its proper localization; HAM-1 is cytoplasmic and is asymmetrically distributed to the posterior of the HSNPHB neuroblast.
45	F15G9.2	F15G9.2	n/a	chrX 9,713,365	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IAW6
46	srb-17	F01D4.7	n/a	chrIV 10,455,510	C. elegans SRB-17 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF03125 (C. elegans Sre G protein-coupled chemoreceptor) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000344 (Nematode chemoreceptor, Sra)
47	srz-61	K03D3.4	n/a	chrIV 16,322,140	C. elegans SRZ-61 protein ;
48	C18D1.2	C18D1.2	n/a	chrII 10,057,912	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)
49	W03F9.4	W03F9.4	n/a	chrV 149,461	contains similarity to Pfam domain PF00755 Choline/Carnitine o-acyltransferase contains similarity to Interpro domains IPR000542 (Acyltransferase ChoActase/COT/CPT), IPR001644 (C3A-anaphylatoxin receptor)
50	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)