UCSC S. cerevisiae Gene Sorter

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UCSC S. cerevisiae Gene Sorter

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#	Name	SGD ORF	Module	BLASTP E-Value	Genome Position	Description
1	HTA1	YDR225W	589	1e-47	chrIV 915,729	Histone H2A, core histone protein required for chromatin assembly and chromosome function one of two nearly identical subtypes (see also HTA2) DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair acetylated by Nat4p
2	FUR4	YBR021W	589	n/a	chrII 282,393	Uracil permease, localized to the plasma membrane expression is tightly regulated by uracil levels and environmental cues
3	PPR1	YLR014C	589	n/a	chrXII 173,625	Zinc finger transcription factor containing a Zn(2)-Cys(6) binuclear cluster domain, positively regulates transcription of genes involved in uracil biosynthesis activity may be modulated by interaction with Tup1p
4	SPS1	YDR523C	589	n/a	chrIV 1,486,302	Putative protein serine/threonine kinase expressed at the end of meiosis and localized to the prospore membrane, required for correct localization of enzymes involved in spore wall synthesis
5	BAS1	YKR099W	589	n/a	chrXI 637,068	Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways also involved in regulation of meiotic recombination at specific genes
6	UBP1	YDL122W	589	n/a	chrIV 243,766	Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins cleaves at the C terminus of ubiquitin fusions irrespective of their size capable of cleaving polyubiquitin chains
7	TCA17	YEL048C	589	n/a	chrV 64,938	Subunit of TRAPPII, a multimeric GEF involved in intra-Golgi and endosome-to-Golgi transport promotes association of TRAPPII-specific subunits with the core complex sedlin related human Sedlin mutations cause SEDT, a skeletal disorder
8	AUR1	YKL004W	589	n/a	chrXI 436,182	Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid synthesis can mutate to confer aureobasidin A resistance
9	RPP1	YHR062C	589	n/a	chrVIII 223,317	Subunit of both RNase MRP and nuclear RNase P RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs
10	TRM5	YHR070W	589	n/a	chrVIII 235,630	tRNA(m(1)G37)methyltransferase, methylates a tRNA base adjacent to the anticodon that has a role in prevention of frameshifting highly conserved across Archaea, Bacteria, and Eukarya
11	SUR2	YDR297W	589	n/a	chrIV 1,057,075	Sphinganine C4-hydroxylase, catalyses the conversion of sphinganine to phytosphingosine in sphingolipid biosyntheis
12	IFH1	YLR223C	589	n/a	chrXII 583,861	Coactivator that regulates transcription of ribosomal protein (RP) genes recruited to RP gene promoters during optimal growth conditions via Fhl1p subunit of CURI, a complex that coordinates RP production and pre-rRNA processing
13	SAP185	YJL098W	589	n/a	chrX 243,670	Protein that forms a complex with the Sit4p protein phosphatase and is required for its function member of a family of similar proteins including Sap4p, Sap155p, and Sap190p
14	FET4	YMR319C	589	n/a	chrXIII 913,709	Low-affinity Fe(II) transporter of the plasma membrane
15	JJJ3	YJR097W	589	n/a	chrX 612,672	Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein
16	IZH1	YDR492W	589	n/a	chrIV 1,435,399	Membrane protein involved in zinc ion homeostasis, member of the four-protein IZH family transcription is regulated directly by Zap1p, expression induced by zinc deficiency and fatty acids deletion increases sensitivity to elevated zinc
17	REX4	YOL080C	589	n/a	chrXV 180,992	Putative RNA exonuclease possibly involved in pre-rRNA processing and ribosome assembly
18	ALR1	YOL130W	589	n/a	chrXV 75,689	Plasma membrane Mg(2+) transporter, expression and turnover are regulated by Mg(2+) concentration overexpression confers increased tolerance to Al(3+) and Ga(3+) ions
19	PPM2	YOL141W	589	n/a	chrXV 57,495	AdoMet-dependent tRNA methyltransferase also involved in methoxycarbonylation required for the synthesis of wybutosine (yW), a modified guanosine found at the 3'-position adjacent to the anticodon of phe-tRNA similarity to Ppm1p
20	BUD21	YOR078W	589	n/a	chrXV 473,047	Component of small ribosomal subunit (SSU) processosome that contains U3 snoRNA originally isolated as bud-site selection mutant that displays a random budding pattern
21	FAL1	YDR021W	589	n/a	chrIV 487,403	Nucleolar protein required for maturation of 18S rRNA, member of the eIF4A subfamily of DEAD-box ATP-dependent RNA helicases
22	RIO1	YOR119C	589	n/a	chrXV 549,519	Essential serine kinase involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA
23	FYV7	YLR068W	589	n/a	chrXII 271,235	Essential protein required for maturation of 18S rRNA required for survival upon exposure to K1 killer toxin
24	YMR185W	YMR185W	589	n/a	chrXIII 630,497	Putative protein of unknown function conflicting evidence on whether null mutant is viable with elongated buds, or inviable
25	YDR491C	YDR491C	589	n/a	chrIV 1,434,745	Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
26	YOL079W	YOL079W	589	n/a	chrXV 181,256	Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
27	YKL083W	YKL083W	589	n/a	chrXI 281,228	Dubious open reading frame, unlikely to encode a protein not conserved in closely related Saccharomyces species partially overlaps the verified essential gene RRP14
28	YCR087W	YCR087W	589	n/a	chrIII 264,233	Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data partially overlaps uncharacterized gene YCR087C-A YCR087W is not an essential gene