UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	sinh-1	Y57A10A.20	0	chrII 12,231,116	sinh-1 encodes the C. elegans ortholog of mammalian SIN1, an essential component of the TORC2 complex that plays a key role in Akt phosphorylation and signaling; in C. elegans, loss of sinh-1 activity via RNAi results in enhanced dauer formation, increased thermotolerance, enhanced stress response, and daf-16-dependent lifespan extension.