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UCSC Genome Browser Gene Interaction Graph
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Gene interactions and pathways from curated databases and text-mining
◀ Back to CTNNB1
CTNNB1 — KDR
Pathways - manually collected, often from reviews:
NCI Pathway Database Signaling events mediated by VEGFR1 and VEGFR2 :
VEGFR2 (dimer)/VEGFA (dimer)/VE-cadherin/beta catenin/alpha catenin complex (KDR-VEGFA-CDH5-CTNNB1-CTNNA1)
→
VE-cadherin/beta catenin/alpha catenin complex (CTNNB1-CTNNA1)
(modification, collaborate)
Carmeliet et al., Cell 1999
physical interaction
NCI Pathway Database Signaling events mediated by VEGFR1 and VEGFR2 :
VEGFR2 (dimer)/VEGFA (dimer)/VE-cadherin/beta catenin/alpha catenin complex (KDR-VEGFA-CDH5-CTNNB1-CTNNA1)
→
VEGFR2 (dimer)/VEGFA (dimer) complex (KDR-VEGFA)
(modification, collaborate)
Carmeliet et al., Cell 1999
physical interaction
NCI Pathway Database Signaling events mediated by VEGFR1 and VEGFR2 :
VE-cadherin/beta catenin/alpha catenin complex (CTNNB1-CTNNA1)
→
VEGFR2 (dimer)/VEGFA (dimer) complex (KDR-VEGFA)
(modification, collaborate)
Carmeliet et al., Cell 1999
physical interaction
NCI Pathway Database Signaling events mediated by VEGFR1 and VEGFR2 :
VE-cadherin/beta catenin/alpha catenin complex (CTNNB1-CTNNA1)
→
VEGFR2 (dimer)/VEGFA (dimer) complex (KDR-VEGFA)
(modification, collaborate)
Carmeliet et al., Cell 1999 , Yamaoka-Tojo et al., Arterioscler Thromb Vasc Biol 2006
physical interaction
NCI Pathway Database Signaling events mediated by VEGFR1 and VEGFR2 :
VE-cadherin/beta catenin/alpha catenin complex (CTNNB1-CTNNA1)
→
VEGFR2 (dimer)/VEGFA (dimer)/IQGAP1/VE-cadherin/beta catenin/alpha catenin complex (KDR-VEGFA-IQGAP1-CDH5-CTNNB1-CTNNA1)
(modification, collaborate)
Carmeliet et al., Cell 1999 , Yamaoka-Tojo et al., Arterioscler Thromb Vasc Biol 2006
physical interaction
NCI Pathway Database Signaling events mediated by VEGFR1 and VEGFR2 :
IQGAP1 (IQGAP1)
→
VEGFR2 (dimer)/VEGFA (dimer)/IQGAP1/VE-cadherin/beta catenin/alpha catenin complex (KDR-VEGFA-IQGAP1-CDH5-CTNNB1-CTNNA1)
(modification, collaborate)
Carmeliet et al., Cell 1999 , Yamaoka-Tojo et al., Arterioscler Thromb Vasc Biol 2006
physical interaction
NCI Pathway Database Signaling events mediated by VEGFR1 and VEGFR2 :
VEGFR2 (dimer)/VEGFA (dimer) complex (KDR-VEGFA)
→
VEGFR2 (dimer)/VEGFA (dimer)/IQGAP1/VE-cadherin/beta catenin/alpha catenin complex (KDR-VEGFA-IQGAP1-CDH5-CTNNB1-CTNNA1)
(modification, collaborate)
Carmeliet et al., Cell 1999 , Yamaoka-Tojo et al., Arterioscler Thromb Vasc Biol 2006
physical interaction
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *