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Vanden Bush et al., Eur J Immunol 2008
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To address this goal, we examined the effects of TLR stimulation on BCR and CD40 induced B cell activation
Ding et al., J Immunol 2009
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After coculture of autoreactive B cells that recognize self-Ag small nuclear ribonucleoprotein particles with activated pDCs, we found that pDCs significantly enhance autoreactive B cell proliferation, autoantibody production, and survival in response to TLR and BCR stimulation
Pone et al., Frontiers in bioscience (Landmark edition) 2012
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Dual BCR/TLR engagement induces CSR to all Ig isotypes, as directed by cytokines, while TLR engagement alone induces marginal CSR