◀ Back to BCR
BCL10 — BCR
Text-mined interactions from Literome
Horita et al., J Exp Med 2000
(Blast Crisis...) :
Here, we show that the interleukin 3-independent expression of the antiapoptotic protein,
Bcl-xL , is
induced by
Bcr-Abl through activation of signal transducer and activator of transcription ( Stat ) 5
Gesbert et al., Blood 2000
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
Bcr/Abl activates transcription of the
Bcl-X gene through STAT5
Petro et al., FEBS Lett 2002
:
However, the mechanism underlying
Bcl-x ( L ) induction in
response to
BCR ligation remains unresolved
Amarante-Mendes et al., Oncogene 1998
:
Interestingly, wild type and mutant
Bcr - Abl induced in HL-60 cells a dramatic down regulation of Bcl-2 and
increased the levels of
Bcl-xL