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CYFIP1 — IGF1

Text-mined interactions from Literome

Takahashi et al., Cell Signal 2010 : Collectively, WAVE2-membrane targeting is directionally controlled by binding of the EB1-stathmin complex to WAVE2 bearing microtubules and by the interaction between WAVE2 and PIP3 produced near IGF-IR that is locally activated by IGF-I
Takahashi et al., Cell Signal 2010 : Suppression of IRSp53 expression by two independent small interfering RNAs ( siRNAs ) completely inhibited IGF-I induced membrane targeting and local accumulation of WAVE2 at the leading edge of cells ... We propose that IRSp53 constitutively forms a complex with WAVE2 and is crucial for membrane targeting followed by local accumulation of WAVE2 at the leading edge of cells through linking WAVE2 to PIP ( 3 ) that is produced near locally activated IGF-IR in response to IGF-I