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CASP3 — WNT1

Text-mined interactions from Literome

Chen et al., J Cell Biol 2001 (Colorectal Neoplasms) : Wnt-1 signaling inhibited the cytochrome c release and the subsequent caspase-9 activation induced by chemotherapeutic drugs, including both vincristine and vinblastine
Shang et al., Cell Signal 2010 : Wnt1 prevents apoptotic demise through the post-translational phosphorylation and maintenance of FoxO3a in the cytoplasm to inhibit an apoptotic cascade that relies upon the loss of mitochondrial membrane permeability, cytochrome c release, Bad phosphorylation, and activation of caspase 3 and caspase 1 as demonstrated by complimentary gene knockdown studies of FoxO3a
Abdul-Ghani et al., Mol Cell Biol 2011 : Wnt11 promotes cardiomyocyte development by caspase mediated suppression of canonical Wnt signals