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CR1 — MAPK15
Text-mined interactions from Literome
Bianco et al., J Biol Chem 1999
:
In conclusion, these data demonstrate that
CR-1 , upon binding to an unknown receptor, can enhance the tyrosine kinase activity of erb B-4 and that a functional erb B-4 receptor is
required for CR-1 induced
MAPK activation
Bianco et al., Cancer Res 2003
(Cell Transformation, Neoplastic) :
However,
CR-1 can also
activate the
mitogen activated protein kinase and Akt pathways independently of Nodal and ALK4 by an unknown mechanism
Bianco et al., Am J Pathol 2008
(Neoplasm Invasiveness) :
Furthermore, coexpression of Cav-1 together with Cr-1 in EpH4 Cr-1/Cav-1 cells inhibited
Cr-1 mediated activation of c-src and
mitogen activated protein kinase signaling pathways
Kannan et al., J Biol Chem 1997
(Breast Neoplasms) :
Finally,
CR-1 was able to
increase p42 ( erk-2 )
mitogen activated protein kinase ( MAPK ) activity in HC-11 cells within 5-10 min of treatment