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MED29 — POLR2H

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind Interaction: Complex of 55 proteins Sato et al., Mol Cell 2004
• IRef Bind Interaction: Complex of 58 proteins Sato et al., Mol Cell 2004
• IRef Bind Interaction: Complex of 71 proteins Sato et al., Mol Cell 2004
• IRef Bind Interaction: Complex of 101 proteins Sato et al., Mol Cell 2004
• IRef Biogrid Interaction: MED29 — POLR2H (physical association, affinity chromatography technology) Sato et al., Mol Cell 2004
• IRef Intact Interaction: Complex of 115 proteins (association, anti tag coimmunoprecipitation) Sato et al., Mol Cell 2004
• IRef Intact Interaction: Complex of 82 proteins (association, anti tag coimmunoprecipitation) Sato et al., Mol Cell 2004
• IRef Intact Interaction: Complex of 64 proteins (association, anti tag coimmunoprecipitation) Sato et al., Mol Cell 2004
• IRef Intact Interaction: Complex of 64 proteins (association, anti tag coimmunoprecipitation) Sato et al., Mol Cell 2004

Text-mined interactions from Literome

Lee et al., Mol Cell Biol 1999 : The Mediator complex of Saccharomyces cerevisiae is required for both general and regulated transcription of RNA polymerase II (PolII) and is composed of two stable subcomplexes ( Srb4 and Rgr1 subcomplexes )
Mittler et al., EMBO Rep 2001 : Novel critical role of a human Mediator complex for basal RNA polymerase II transcription
Sato et al., Mol Cell 2004 : The Mediator is a multiprotein transcriptional coactivator that is expressed ubiquitously in eukaryotes from yeast to mammals and is required for induction of RNA polymerase II (pol II) transcription by DNA binding transcription factors
Takagi et al., J Biol Chem 2006 : Taken together, these findings lead to the suggestion that Mediator is required for basal RNA polymerase II transcription in vivo
Thiaville et al., Nucleic Acids Res 2008 : It is unclear whether Mediator complex in yeast is necessary for all RNA polymerase II (Pol II) transcription or if it is limited to genes activated by environmental stress
Carey et al., Cold Spring Harbor protocols 2010 : INTRODUCTION : The Mediator ( Med ) complex plays a key role in promoter-specific activation of transcription by RNA polymerase II (Pol II)
Han et al., Mol Cell Biol 1999 : The multisubunit Mediator complex of Saccharomyces cerevisiae is required for most RNA polymerase II (Pol II) transcription