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HDAC1 — IL2
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Gray et al., Cytokine 2000
:
Our results indicate that in contrast to the mouse,
HDAC1 is not
inducible by
IL-2
Endt et al., Eur J Immunol 2007
:
IL-2 stimulation
leads to an up-regulation of
SAP expression, which can be enhanced by IL-12, the stimulation of TLR3 by polyinosinic-polycytidylic acid ( poly ( I:C ) ) and to a lesser extent by IFN-alpha
Matsuoka et al., Biochem Pharmacol 2007
:
Previous studies have shown that
HDAC inhibitors selectively
inhibit IL-2 gene expression, but the mechanism of this inhibition remains to be elucidated
Matsuoka et al., Biol Pharm Bull 2008
(Thrombocytopenia) :
Histone deacetylase (HDAC) inhibitors
repress interleukin-2 (IL-2) gene expression in T cells and possess immunosuppressive activity in vivo
Nayak et al., J Biol Chem 2009
:
Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and
interleukin-2 repression by
histone deacetylase
Rehni et al., Naunyn Schmiedebergs Arch Pharmacol 2012
(Opioid-Related Disorders...) :
The present study has been designed to investigate the effect of selective inhibitors of
histone deacetylase and/or N-acetyl-Asp-Glu-Val-Asp-al ( Ac-DEVD-CHO ), a selective
interleukin-1ß converting enzyme
inhibitor , on the development of naloxone induced opioid withdrawal syndrome both in vitro and in vivo and the effect of histone deacetylase inhibition on histone H3 acetylation in brain
Vitoriano-Souza et al., PloS one 2012
:
With regard to cytokines, the
SAP led to production of
interleukin (IL)-2 , IL-6, and IL-4