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FOS — NOTCH2
Text-mined interactions from Literome
Talora et al., Genes Dev 2002
(Cell Transformation, Neoplastic...) :
Increased Notch1 signaling, but not
Notch2 ,
causes a dramatic down-modulation of HPV-driven transcription of the E6/E7 viral genes, through suppression of
AP-1 activity by up-regulation of the Fra-1 family member and decreased c-Fos expression
Henken et al., Cellular oncology (Dordrecht) 2012
(Cell Transformation, Neoplastic...) :
Moderate
Notch expression
led to an increased
AP-1 transcriptional activity and DNA binding activity, but did not affect complex composition