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CCND1 — TCF12

Text-mined interactions from Literome

Tetsu et al., Nature 1999 (Colonic Neoplasms) : Furthermore, expression of a dominant negative form of TCF in colon-cancer cells strongly inhibits expression of cyclin D1 without affecting expression of cyclin D2, cyclin E, or cyclin dependent kinases 2, 4 or 6
Rhee et al., Oncogene 2002 (Carcinoma, Squamous Cell...) : Treatment of one HNSCC cell line ( SNU 1076 ) with anti-Wnt-1 antibodies reduced the activity of the Wnt/Fz dependent transcription factor LEF/TCF , and diminished the expression of cyclin D1 and beta-catenin proteins
Li et al., Genomics 2004 : The strong binding of E2F1 and NFkappaB is especially noteworthy, because the former transcription factor is regulated by cyclin D1 , a downstream target of beta-catenin/TCF/LEF signaling, whereas the latter transcription factor has been implicated in `` cross talk '' between the Wnt and the NFkappaB signaling pathways
Jung et al., Cancer Res 2004 (Prostatic Neoplasms) : Because cyclin D1 is mainly regulated by beta-catenin/T-cell factor ( TCF ) , TCF-4 response element was used in a reporter gene transcription assay, demonstrating that HOXB13 significantly inhibits TCF-4 mediated transcriptional activity in both prostate and nonprostate cells
Ho et al., Toxicol Appl Pharmacol 2005 (Lung Neoplasms) : The increased cyclin D1 protein level was induced through activation of the transcription factor , nuclear factor kB ( NFkappaB ), in the NHBE cells
Sourisseau et al., Mol Cell Biol 2006 : Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1 regulated transcription factor ZONAB/DbpA
Katoh et al., Cancer Biol Ther 2007 (Helicobacter Infections...) : WNT-beta-catenin-TCF/LEF signaling induces upregulation of MYC, CCND1 , WISP1, FGF20, JAG1 and DKK1 genes ... WNT-beta-catenin-TCF/LEF signaling induces upregulation of MYC, CCND1 , WISP1, FGF20, JAG1 and DKK1 genes
Budhram-Mahadeo et al., Oncogene 2008 (Breast Neoplasms...) : Proliferation associated Brn-3b transcription factor can activate cyclin D1 expression in neuroblastoma and breast cancer cells
Mikheev et al., Breast Cancer Res Treat 2008 : Consistent with the results of these transient transfection assays, we were unable to demonstrate the expected beta-catenin dependent , TCF/Lef mediated inhibition of cyclin D1 and c-myc gene transcription in breast cells overexpressing DKK-1
Taurin et al., Am J Physiol Cell Physiol 2008 : Using the PKA inhibitor PKI or dominant negative TCF-4 mutant, we show that ATP induced cyclin D1 promoter activation, cyclin D1 protein expression, and proliferation of VSMC are all dependent on PKA and TCF activities
Zhang et al., J Biol Chem 2012 (Colonic Neoplasms) : We find that knockdown of PAX2 inhibits the activity of AP-1, a transcription factor that induces cyclin D1 expression, implying that PAX2 induces cyclin D1 through AP-1
Schulze et al., Oncogene 1994 : Activation of the E2F transcription factor by cyclin D1 is blocked by p16INK4, the product of the putative tumor suppressor gene MTS1