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TLR2 — VDR

Text-mined interactions from Literome

Liu et al., Science 2006 (Disease Susceptibility...) : We report here that TLR activation of human macrophages up-regulated expression of the vitamin D receptor and the vitamin D-1-hydroxylase genes, leading to induction of the antimicrobial peptide cathelicidin and killing of intracellular Mycobacterium tuberculosis
Adams et al., J Immunol 2009 (Vitamin D Deficiency) : In monocytes/macrophages, this occurs primarily in response to activation of TLR , that induce expression of the vitamin D receptor and localized synthesis of 1,25 ( OH ) ( 2 ) D from precursor 25-hydroxyvitamin D ( 3 ) ( 25OHD )