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IL2 — SEA
Text-mined interactions from Literome
Koyanagi et al., Int Immunol 2004
:
SEA induced
IL-2 production was weaker in neonatal thymic blasts than in the adult splenic CD4 SP T cell blasts
Saito et al., Microbiol Immunol 1991
:
All the transfectants supported
SEA induced
IL-2 production by human T cells
Huang et al., Acta Biochim Biophys Sin (Shanghai) 2007
:
Repeated
SEA stimulation
led to down-regulation of
interleukin (IL)-2 , and high levels of IL-10
Kato et al., Immunobiology 1990
:
The result showed that the SEA induced IFN-gamma production was observed in spite of suppression of
SEA induced
IL-2 production in spleen cells from BCG immunized B6 mice ... On the contrary, the depressed IFN production was observed in spite of high
SEA induced
IL-2 production in spleen cells from their control mice
Li et al., Zhonghua Yi Xue Za Zhi 1990
(Schistosomiasis japonica) :
It was found that the activity of IL-1 was greatly increased and positively related to the body temperature, and high level of
IL-2 was
induced by SWAP and
SEA in the group of acute schistosomiasis ... The level of
IL-2 induced by SWAP and
SEA in the groups of chronic and advanced schistosomiasis was significantly lower than that in the group of acute schistosomiasis, but was much higher than that in the group of normal control ... The level of
IL-2 induced by SWAP and
SEA in the cases of acute schistosomiasis was positively related to the activity of IL-1
Ferreira et al., Mem Inst Oswaldo Cruz 2012
(Chronic Disease...) :
We demonstrate that stimulation with
SEA induced prominent lymphocyte proliferation and high levels of tumour necrosis factor (TNF)-a,
interleukin (IL)-4 and IL-10 secretion in both OST and non infected individuals ( NI )
Carlsson et al., Scand J Immunol 1987
:
The collective data show that the
SEA induced suppression of
IL-2 activity in lymphocyte culture medium is not due to a suppression of the IL-2 production but rather depends on depletion of IL-2 due to absorption of IL-2 from the culture medium
Ohta et al., J Immunol 1988
(Granuloma...) :
We observed that four of eight clones tested produced
IL-2 in
response to
SEA , and three of them were able to transfer S. japonicum egg-specific granulomatous hypersensitivity in vitro to an HLA haplo-identical individual without previous schistosome infection
Stavitsky et al., Infect Immun 1989
(Chronic Disease...) :
In vitro
SEA induced
IL-2 production by HG cells from acutely infected mice was suppressed consistently by Lyt-2+ T cells from the spleens and in the majority of our experiments by Lyt-2+ T cells from the HG of mice infected for 10 weeks
Fischer et al., J Immunol 1989
:
Both the G8 mAb and an anti-HLA-DR mAb 9-49 inhibited
SEA binding to accessory cells and also
inhibited SEA induced, but not PHA induced, T cell proliferation and production of
IL-2
Carlsson et al., Cell Immunol 1985
:
Histamine inhibited the production of interferon-gamma and
interleukin 2 (IL-2) induced in human peripheral blood mononuclear cells by
Staphylococcal Enterotoxin A (SEA) but had no effect on the expression of IL-2 receptors
Carlsson et al., Cell Immunol 1985
:
Staphylococcal Enterotoxin A (SEA) at picogram amounts
induces high levels of
interleukin 2 (IL-2) and interferon in human mononuclear cells ...
SEA is a stronger
inducer of
IL-2 than phytohemagglutinin, leukoagglutinin, and concanavalin A
Yokomizo et al., J Vet Med Sci 1995
:
SEA , SEB, SEC and TSST-1, all
induced the in vitro release of
interleukin-2 , interferon gamma and tumor necrosis factor alpha in a dose dependent manner
Reid et al., Drug Chem Toxicol 1994
:
Staphylococcal enterotoxin A (SEA) is both a potent mitogen and the most potent in vitro
inducer of
IL-2 production that has been described
Hedlund et al., Cancer Immunol Immunother 1993
(Neoplasms, Experimental) :
SEA induced
interleukin-2 receptor expression and proliferation in both CD4+ and CD8+ T cells
Hobeika et al., Biochem Biophys Res Commun 1996
:
A synthetic peptide of this region, SEA ( 121-149 ), blocks
SEA binding to class II MHC molecules and
induces interleukin-1 and tumor necrosis factor production in monocytes
Gerwien et al., Tissue Antigens 1998
:
In a SEA `` non-responder '' T-cell clone obtained from the affected skin of a patient with psoriasis vulgaris,
SEA does not
inhibit IL-2Rbeta expression and IL-15-driven proliferation
Srinivas et al., Scand J Immunol 1998
:
Stimulation of PBM by
SEA resulted in increased levels of IL-1beta,
IL-2 and interferon (IFN)-gamma after 24h