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CD47 — IL2
Text-mined interactions from Literome
Rebres et al., J Biol Chem 2001
:
A mutant form of
CD47 without its Ig domain that did not induce actin polymerization or localize to rafts still enhanced T cell receptor ( TCR ) -dependent tyrosine phosphorylation of PLCgamma and associated Ca ( 2+ ) signaling but did not
augment IL-2 secretion
Avice et al., J Immunol 2001
:
We recently reported that
CD47 ligation
inhibited IL-2 release by umbilical cord blood mononuclear cells activated in the presence of IL-12, but not IL-4, preventing the induction of IL-12Rbeta(2) expression and the acquisition of Th1, but not the Th2 phenotype