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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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A2M — IL2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Bauer et al., FEBS Lett 1985 : Murine interleukin 1 stimulates alpha 2-macroglobulin synthesis in rat hepatocyte primary cultures
Borth et al., Immunology 1986 : The loss of the biological activity of interleukin-2 ( IL-2, T-cell growth factor ) in the presence of alpha 2-macroglobulin-trypsin ( alpha 2M.t ) complexes has been investigated using an IL-2 dependent cloned ` cytotoxic ' murine T-cell line
Warburton et al., FEBS Lett 1993 : Interleukin-1 beta, interleukin-6 and transforming growth factor-beta synergize with hydrocortisone, increasing the synthesis of alpha 2-macroglobulin 2- to 4-fold, although they have no effect in the absence of hydrocortisone