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SMN1 — STAT3
Text-mined interactions from Literome
Pechkovsky et al., Am J Pathol 2012
(Idiopathic Pulmonary Fibrosis) :
Suppression of
STAT3 signaling diminished resistance of IPF LFs to staurosporine induced apoptosis and responsiveness to transforming growth factor ß ( 1 ) but
increased basal
a-SMA and restored ß ( 3 ) integrin expression in LFs via an ALK-5 dependent, SMAD3/7 independent mechanism
Wu et al., Cell Biochem Funct 2013
:
If we inhibit
STAT3 activity by STAT3 targeted small molecules, TSLP induced
a-SMA and collagen I upregulation can not be
detected