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NFKB1 — TRAM1
Text-mined interactions from Literome
Li et al., J Mol Med (Berl) 2005
:
LPS induced, TLR4 mediated signaling employs multiple TIR-domain containing adaptors, MyD88/TIRAP to
mediate NFkappaB activation,
TRIF/TRAM for IRF3 activation
Bulut et al., J Biol Chem 2005
(Inflammation) :
Mycobacterial heat shock protein 65-induced
NF-kappaB activation was MyD88-, TIRAP-, TRIF-, and
TRAM dependent and required the presence of MD-2
Seki et al., Hepatology 2008
(Acute Disease...) :
Toll-like receptors ( TLRs ) are pattern recognition receptors that recognize pathogen associated molecular patterns and signal through adaptor molecules, myeloid differentiation factor 88 ( MyD88 ), Toll/IL-1 receptor domain containing adaptor protein ( TIRAP ), Toll/IL-1 receptor domain containing adaptor inducing interferon-beta ( TRIF ), and
TRIF related adaptor molecule ( TRAM ) to
activate transcription factors,
nuclear factor (NF)-kappaB , activator protein 1 (AP-1), and interferon regulatory factors ( IRFs ) leading to the initiation of innate immunity