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POLDIP2 — TNFSF11
Text-mined interactions from Literome
Kim et al., Mol Pharmacol 2007
(Calcium Signaling) :
Subsequent characterization of the DMS mediated suppression of osteoclastogenesis revealed that DMS did not affect
RANKL induced activation of JNK,
p38 , NF-kappaB, and Ca2+ oscillation
Murakami et al., Biofactors 2007
:
RANKL-up regulated extracellular signal regulated kinase ( ERK ) 1/2 and
p38 mitogen activated protein kinase ( MAPK ) activities were attenuated by PEITC, whereas c-Jun N-terminal kinase (JNK1/2) activation was increased
Tsai et al., Eur J Pharmacol 2008
:
Our data suggest that paeonol inhibits osteoclastogenesis from bone marrow stromal cells and macrophage cells via attenuated of
RANKL induced ERK,
p38 and NF-kappaB activation, which in turn protect bone loss from ovariectomy
Hasegawa et al., Biol Pharm Bull 2010
(Bone Resorption) :
In experiments to elucidate its mechanism of action, honokiol was found to suppress
RANKL induced phosphorylation of
p38 mitogen activated protein kinase ( MAPK ), extracellular signal regulated kinase ( ERK ), and c-Jun N-terminal kinase (JNK)