Huo et al., Biol Reprod 2004
(MAP Kinase Signaling System) :
Both U0126 and roscovitine inhibited the phosphorylation of MAPK and p90rsk, and the synthesis of cyclin B1 stimulated by proteasome inhibitors
Smythe et al., Mol Reprod Dev 2005
:
Inhibition of MAPK signaling by U0126 was capable of delaying but not permanently blocking Cdc2/cyclin B activation and GVBD in 5-HT treated oocytes and subsets of NSW treated oocytes