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CDH1 — VIM
Text-mined interactions from Literome
Avizienyte et al., Mol Biol Cell 2004
(Colonic Neoplasms...) :
Here we show that the SH2 and SH3 domains of Src mediate peripheral accumulation of phospho-myosin, leading to integrin adhesion complex assembly, whereas loss of SH2 or SH3 function restores normal regulation of
E-cadherin and
inhibits vimentin expression
Chua et al., Oncogene 2007
(Cell Transformation, Neoplastic...) :
Using parental MCF10A cells and a variant that expresses the myoepithelial marker p63 stably overexpressing the constitutively active p65 subunit of NF-kappaB ( MCF10A/p65 ), we show that NF-kappaB suppresses the expression of epithelial specific genes
E-cadherin and desmoplakin and
induces the expression of the mesenchymal specific gene
vimentin
Veena et al., Lab Invest 2009
(Carcinoma, Non-Small-Cell Lung...) :
CAR expression is associated with an absence of
E-cadherin , diminished expression of alpha- and gamma-catenin, and
increased Zeb1, Snail, and
vimentin expression in lung cancer cells ... CAR expression is associated with an absence of
E-cadherin , diminished expression of alpha- and gamma-catenin, and
increased Zeb1, Snail, and
vimentin expression in lung cancer cells
Chen et al., Chinese journal of cancer 2010
(Breast Neoplasms) :
Immunofluorescence, Western blot, real-time PCR revealed that compared with parent cell MCF-7, after transfected with Snail, the expression of
E-cadherin in MCF-7 decreased, but Snail,
Vimentin , and BCRP
increased
Barnett et al., Biochem Biophys Res Commun 2011
(Prostatic Neoplasms) :
An EMT model created by Snail overexpression in ARCaP cells was associated with decreased
E-cadherin and
increased vimentin
Grandclement et al., PloS one 2011
(Cell Transformation, Neoplastic...) :
Treatment with specific TGFß-type1 receptor kinase inhibitors restored
E-cadherin levels and
inhibited in part neuropilin-2 induced
vimentin expression, suggesting that neuropilin-2 cooperates with TGFß-type1 receptor to promote epithelial-mesenchymal transition in colorectal cancer cells
Adhim et al., Br J Cancer 2011
(Urinary Bladder Neoplasms) :
Etodolac reduced SNAIL mRNA and
vimentin cell surface expression, and
induced E-cadherin mRNA and
E-cadherin cell surface expression, in T24
Matsushita et al., Ann Surg Oncol 2012
(Colorectal Neoplasms...) :
Recombinant soluble CXCL16 promoted the epithelial-mesenchymal transition (EMT) phenotype characterized by impaired
E-cadherin production and
induction of
vimentin in vitro
Xu et al., Hepatogastroenterology 2012
(Carcinoma, Hepatocellular...) :
The expression of
E-cadherin was decreased but the expression of
vimentin increased ; also, the migratory capability was increased by 2.1±0.19-fold as compared with untreated cells
Qi et al., PloS one 2012
(Brain Neoplasms...) :
Lowered expression of ZEB2 enhanced
E-cadherin levels but also
inhibited ß-Catenin,
Vimentin , N-cadherin, and Snail expression
Chen et al., J Ethnopharmacol 2012
(Pulmonary Fibrosis) :
In a fibrotic cell model with transforming growth factor beta-1 induction, the human lung epithelial A549 acquired a mesenchymal phenotype and an
increase of
vimentin expression with a concomitant decrease of
E-cadherin
Lee et al., Biochem Biophys Res Commun 2013
(MAP Kinase Signaling System...) :
Slug expression was required for cell migration and
E-cadherin reduction/vimentin induction induced by Gas6
Miao et al., Med Oncol 2013
:
Enhanced DDR1 expression mediated by collagen I could activate MMP-2, N-cadherin and vimentin expression, but reduce E-cadherin expression ; however, inhibition of DDR1 expression could suppress MMP-2, N-cadherin and
vimentin expression and
induce E-cadherin activation
Lu et al., Evidence-based complementary and alternative medicine : eCAM 2013
:
AIMs suppressed
vimentin , N-cadherin, and ß-catenin expression and
induced E-cadherin