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CDH1 — RBBP4
Text-mined interactions from Literome
Peinado et al., Mol Cell Biol 2004
:
Here we show that mammalian Snail
requires histone deacetylase (HDAC) activity to repress
E-cadherin promoter and that treatment with trichostatin A (TSA) is sufficient to block the repressor effect of Snail
Witta et al., Cancer Res 2006
(Carcinoma, Non-Small-Cell Lung...) :
The zinc finger transcriptional repressor, ZEB1,
inhibits E-cadherin expression by recruiting
histone deacetylases (HDAC)
Villar et al., Infect Immun 2007
(Candidiasis, Oral) :
Mucosal tissue invasion by Candida albicans is associated with
E-cadherin degradation,
mediated by transcription factor Rim101p and protease
Sap5p
Iacopino et al., Int J Oncol 2008
(Prostatic Neoplasms) :
The goal of this study was to assess the
effects of an
HDAC inhibitor, valproic acid ( VA ), on proliferation, androgen-sensitivity, androgen receptor levels and
E-cadherin ( E-cad ) expression in human prostate cancer cells
Thomas et al., Bioorg Med Chem 2008
(Lung Neoplasms) :
Prodrug incubation with beta-glucuronidase in the culture media led efficiently to the release of the parent drug and thereby restoring its ability to decrease cell proliferation, to inhibit
HDAC and to
induce E-Cadherin expression
von Burstin et al., Gastroenterology 2009
(Lung Neoplasms...) :
In line, mesenchymal pancreatic cancer specimens and primary cell lines from genetically engineered Kras ( G12D ) mice showed
HDAC dependent down-regulation of
E-cadherin and high metastatic potential
Kakihana et al., J Thorac Oncol 2009
(Carcinoma, Non-Small-Cell Lung...) :
In contrast to H460 and H661, H157 cells were resistant to
E-cadherin up-regulation by
HDAC inhibitors
Huang et al., Mol Pharmacol 2011
:
This finding, together with the
HDAC inhibitor
induced up-regulation of KLF4 and
E-cadherin , suggests that HDAC inhibitors could activate the expression of these genes through changes in histone methylation status ... This finding, together with the
HDAC inhibitor
induced up-regulation of KLF4 and
E-cadherin , suggests that HDAC inhibitors could activate the expression of these genes through changes in histone methylation status
Yi et al., Chemotherapy 2012
(Carcinoma...) :
DNMT inhibitors and
HDAC inhibitors
regulate E-cadherin and Bcl-2 expression in endometrial carcinoma in vitro and in vivo
Nagathihalli et al., Mol Cancer Ther 2012
(Carcinoma, Non-Small-Cell Lung...) :
Smoking induces epithelial-to-mesenchymal transition in non-small cell lung cancer through
HDAC mediated downregulation of
E-cadherin
Iordache et al., International journal of molecular sciences 2012
:
RT-PCR assay showed that
HDAC inhibitors
down-regulated the expression of endothelial genes such as
VE-cadherin , CD133, CXCR4 and Tie-2