Yu et al., Cytotechnology 2009
:
Matrine significantly reduced the invasion, MMP-9/MMP-2 activation , Akt phosphorylation, nuclear factor kappaB p-65 expression and DNA binding activity, and mRNA levels of MMP-9, MMP-2, EGF and VEGFR1 in MDA-MB-231 cells
Wang et al., Circ Res 1998
:
These data suggest the role of flt-1 in mediating VEGF stimulated MMP expression of SMCs