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PRKACB — WNK1
Text-mined interactions from Literome
Takahashi et al., Eur J Biochem 2002
(MAP Kinase Signaling System) :
Overexpression of coactivators, CBP ( CREB binding protein ) and p300, failed to reverse the
PKA mediated inhibition of
p65 transactivation
Gao et al., J Biol Chem 2010
(Breast Neoplasms) :
In this study, we have demonstrated the effect of PKA on NF-kappaB activity in view of AKIP1 action ; and in 293 and HeLa cells, where the endogenous AKIP1 expression is minimal, PKA activating agents inhibited the NF-kappaB dependent reporter gene expression, blocked the interaction of PKAc and p65 subunit of NF-kappaB, and attenuated
PKA dependent phosphorylation of
p65 on Ser-276