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KCNQ1 — PRKACB

Pathways - manually collected, often from reviews:

• KEGG Vibrio cholerae infection: KCNQ1 → PRKACA/PRKACB/PRKACG/PRKX (protein-protein, compound)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• MIPS CORUM KCNQ1 macromolecular complex: KCNQ1 macromolecular complex complex (AKAP9-KCNQ1-PPP1CA-PPP1CB-PPP1CC-PRKACA-PRKACB-PRKACG-PRKAR2A-PRKAR2B) Marx et al., Science 2002
• IRef Corum Interaction: Complex of 21 proteins (association, pull down) Marx et al., Science 2002

Text-mined interactions from Literome

Nicolas et al., Cardiovasc Res 2008 : We propose that the KCNQ1-KCNE1 channel directly interacts with microtubules and that this interaction plays a major role in coupling PKA dependent phosphorylation of KCNQ1 with I ( Ks ) activation
Li et al., J Biol Chem 2012 (Long QT Syndrome) : Human mutations that disrupt I ( Ks ) -Yotiao interaction result in reduced PKA dependent phosphorylation of the I ( Ks ) subunit KCNQ1 and inhibition of sympathetic stimulation of I ( Ks ), which can give rise to long-QT syndrome