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CTR9 — NOX5

Text-mined interactions from Literome

Si et al., Am J Physiol Gastrointest Liver Physiol 2008 (Adenocarcinoma...) : STAT5 mediates PAF induced NADPH oxidase NOX5-S expression in Barrett 's esophageal adenocarcinoma cells ... STAT5 mediates PAF induced NADPH oxidase NOX5-S expression in Barrett 's esophageal adenocarcinoma cells ... PAF dependent induction of NOX5-S expression and H ( 2 ) O ( 2 ) production were significantly decreased by the MAPK kinase 1 inhibitor PD-98059, by the cytosolic phospholipase A ( 2 ) ( cPLA(2) ) inhibitor AACOCF3, and by STAT5 downregulation with STAT5 siRNA ... We conclude that acid induced NOX5-S expression and H ( 2 ) O ( 2 ) production is mediated in part by production of PAF in SEG1 EA cells, and that PAF induced increase in NOX5-S expression depends on sequential activation of ERK MAP kinases, cPLA(2), and STAT5 in these cells
Fiorini et al., FEBS Lett 1990 : In the presence of NADPH-oxidase inhibitor DPI, only PAF induces changes in rs values
Barnett et al., J Surg Res 1997 : beta-Adrenergic stimulation of PMNs enhances cAMP dependent protein kinase A (PKA) activity and has been shown to inhibit PAF mediated NADPH-oxidase activity