Lu et al., Cytokine 2005
:
Co-transfection studies showed that HDAC1 had a repressing effect on the activity of IL-12 p40 promoter
Endt et al., Eur J Immunol 2007
:
IL-2 stimulation leads to an up-regulation of SAP expression, which can be enhanced by IL-12 , the stimulation of TLR3 by polyinosinic-polycytidylic acid ( poly ( I:C ) ) and to a lesser extent by IFN-alpha