UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to MTOR

MTOR — TERT

Pathways - manually collected, often from reviews:

NCI Pathway Database Regulation of Telomerase: Telomerase complex (TERT-PTGES3) → Telomerase/AKT1/mTOR/p70S6K complex (AKT1-MTOR-RPS6KB1-HSP90AA1-TERT-PTGES3-DKC1) (modification, collaborate)
Haendeler et al., FEBS Lett 2003
Evidence: assay
NCI Pathway Database Regulation of Telomerase: Telomerase complex (TERT-PTGES3) → mTOR (MTOR) (modification, collaborate) Haendeler et al., FEBS Lett 2003
Evidence: assay
NCI Pathway Database Regulation of Telomerase: Telomerase/AKT1/mTOR/p70S6K complex (AKT1-MTOR-RPS6KB1-HSP90AA1-TERT-PTGES3-DKC1) → AKT1 (AKT1) (modification, collaborate) Haendeler et al., FEBS Lett 2003
Evidence: assay
NCI Pathway Database Regulation of Telomerase: Telomerase/AKT1/mTOR/p70S6K complex (AKT1-MTOR-RPS6KB1-HSP90AA1-TERT-PTGES3-DKC1) → p70S6K (RPS6KB1) (modification, collaborate) Haendeler et al., FEBS Lett 2003
Evidence: assay
NCI Pathway Database Regulation of Telomerase: Telomerase/AKT1/mTOR/p70S6K complex (AKT1-MTOR-RPS6KB1-HSP90AA1-TERT-PTGES3-DKC1) → mTOR (MTOR) (modification, collaborate) Haendeler et al., FEBS Lett 2003
Evidence: assay
NCI Pathway Database IL2 signaling events mediated by PI3K: TERT (TERT) → AKT1/mTOR/p70S6K/Hsp90/TERT complex (AKT1-MTOR-RPS6KB1-HSP90AA1-TERT) (modification, collaborate)
Kawauchi et al., J Immunol 2005
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database IL2 signaling events mediated by PI3K: TERT (TERT) → mTOR (MTOR) (modification, collaborate) Kawauchi et al., J Immunol 2005
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database IL2 signaling events mediated by PI3K: Hsp90 (HSP90AA1) → AKT1/mTOR/p70S6K/Hsp90/TERT complex (AKT1-MTOR-RPS6KB1-HSP90AA1-TERT) (modification, collaborate)
Kawauchi et al., J Immunol 2005
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database IL2 signaling events mediated by PI3K: AKT1 (AKT1) → AKT1/mTOR/p70S6K/Hsp90/TERT complex (AKT1-MTOR-RPS6KB1-HSP90AA1-TERT) (modification, collaborate)
Kawauchi et al., J Immunol 2005
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database IL2 signaling events mediated by PI3K: AKT1/mTOR/p70S6K/Hsp90/TERT complex (AKT1-MTOR-RPS6KB1-HSP90AA1-TERT) → mTOR (MTOR) (modification, collaborate) Kawauchi et al., J Immunol 2005
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database IL2 signaling events mediated by PI3K: AKT1/mTOR/p70S6K/Hsp90/TERT complex (AKT1-MTOR-RPS6KB1-HSP90AA1-TERT) → p70S6K (RPS6KB1) (modification, collaborate) Kawauchi et al., J Immunol 2005
Evidence: mutant phenotype, assay, physical interaction

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Biogrid Interaction: TERT — MTOR (physical association, affinity chromatography technology) Kawauchi et al., J Immunol 2005