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MTOR — RPS6KB2

Pathways - manually collected, often from reviews:

• KEGG mTOR signaling pathway: MTOR → RPS6KB1/RPS6KB2 (protein-protein, phosphorylation)
• KEGG Insulin signaling pathway: MTOR → RPS6KB1/RPS6KB2 (protein-protein, activation)
• KEGG Acute myeloid leukemia: MTOR → RPS6KB1/RPS6KB2 (protein-protein, activation)
• KEGG ErbB signaling pathway: MTOR → RPS6KB1/RPS6KB2 (protein-protein, activation)
• WikiPathways Focal Adhesion-PI3K-Akt-mTOR-signaling pathway: MLST8/MTOR/RPTOR → RPS6KB2/RPS6KB1 (activation)
• WikiPathways Insulin Signaling: MTOR → RPS6KB2/RPS6KB1 (activation)
• WikiPathways Angiopoietin Like Protein 8 Regulatory Pathway: Complex of RPTOR-MLST8-MTOR → RPS6KB2/RPS6KB1 (mim-conversion)
• WikiPathways AMP-activated Protein Kinase (AMPK) Signaling: Complex of MTOR-RPTOR → RPS6KB1/RPS6KB2 (activation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: RPS6KB2 — MTOR (in vitro) Minami et al., Genes Cells 2001*

Text-mined interactions from Literome

Cruz et al., J Leukoc Biol 2005 : We show that S6K2 is activated by IL-3 in the IL-3 dependent Ba/F3 cell line and that this is mediated by mTOR and its upstream activator PI-3K but not by the MAPK kinase/extracellular signal regulated kinase pathway
Magnuson et al., Biochem J 2012 : mTORC1 ( mammalian TORC1 ) phosphorylates and activates S6K1 and S6K2 , whose first identified substrate was rpS6 ( ribosomal protein S6 ), a component of the 40S ribosome