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MAPK8 — PXN
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Vadlamudi et al., Oncogene 1999
(Breast Neoplasms) :
The HRG induced increase in serine phosphorylation of
paxillin and cell scattering were selectively
inhibited by a specific inhibitor of
p38MAPK or a dominant negative p38MAPK mutant, but not by inhibitors of p42/44MAPK or PI-3 kinase pathways
Metalli et al., Am J Pathol 2010
(Cell Transformation, Neoplastic...) :
The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and
mitogen activated protein kinase dependent
activation of
paxillin
Sen et al., J Clin Invest 2012
(MAP Kinase Signaling System...) :
We show that androgen and EGF promoted
MAPK dependent phosphorylation of
paxillin , resulting in nuclear translocation of paxillin
Genua et al., PloS one 2012
(Carcinoma...) :
These effects require IGF-I induced Akt- and
MAPK dependent activation of
paxillin
Takahashi et al., FEBS Lett 1996
:
Angiotensin II (Ang II), a potent hypertrophic factor for vascular smooth muscle cells ( VSMC ),
induces activation of the ras proto-oncogene product ( Ras ) and
mitogen activated protein ( MAP ) kinases , and tyrosine phosphorylation of a focal adhesion associated protein,
paxillin
Herrera et al., J Cell Sci 1998
:
This event correlated with increased tyrosine phosphorylation of
paxillin and
activation of
MAPK