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ATR — POT1

Text-mined interactions from Literome

Palm et al., Mol Cell Biol 2009 : In contrast to the repression of ATR signaling by POT1a , the ability of POT1b to control 5'-end resection was found to require two regions in the C terminus, one corresponding to the TPP1 binding domain and a second representing a new domain located between amino acids ( aa ) 300 and 350
Gong et al., Mol Cell 2010 : In S/G2, RPA was readily detectable at dysfunctional telomeres, and both POT1a and POT1b were required to exclude RPA and prevent ATR activation ... In G1, the accumulation of RPA at dysfunctional telomeres was strikingly less, and POT1a was sufficient to repress ATR signaling
Thanasoula et al., EMBO J 2012 : Shelterin component TRF2 prevents ATM activation, while POT1 represses ATR signalling at telomeres