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CASP7 — SOD2
Text-mined interactions from Literome
Noshita et al., J Cereb Blood Flow Metab 2001
(Ischemic Attack, Transient) :
The current study revealed
Mn-SOD might
affect cytochrome c translocation and downstream
caspase activation in the mitochondrial dependent cell death pathway after transient FCI
Sakudo et al., Biochem Biophys Res Commun 2003
:
Re-introduction of Prnp rescued cells from apoptosis, upregulated
superoxide dismutase ( SOD ) activity, enhanced superoxide anion elimination, and
inhibited caspase-3/9 activation
Yoshida et al., Lab Invest 2003
:
Accordingly, neither
superoxide dismutase nor N ( G ) -monomethyl-L-arginine
had significant effects on HRPE cell apoptosis or
caspase-3 activation
Elner et al., Trans Am Ophthalmol Soc 2003
:
Accordingly, neither
SOD nor NO inhibitors
had significant effects on HRPE cell apoptosis or
caspase-3 activation
Conde de la Rosa et al., J Hepatol 2006
(MAP Kinase Signaling System...) :
( 3 )
PEG-SOD prevents ERK1/2-, JNK- phosphorylation,
caspase activation and apoptosis induced by menadione
Vincent et al., Exp Neurol 2007
(Diabetes Mellitus...) :
We demonstrate that overexpression of
SOD2 decreases superoxide ( O ( 2 ) ( - ) ) in cultured primary dorsal root ganglion ( DRG ) neurons and subsequently
blocks caspase-3 activation and cellular injury
GarcĂa-Berrocal et al., J Laryngol Otol 2010
(Disease Models, Animal) :
Inhibition of
caspase-3 activity significantly
reduced cochlear heat shock protein 70 expression and total
superoxide dismutase activity, and improved auditory brainstem response and auditory steady state response thresholds
Wang et al., J Biol Chem 2011
(Disease Models, Animal...) :
By contrast, ectopic Drosophila
Sod2 expression and antioxidant treatment
reduced ROS and
caspase 3 activity and extended the life span of the SCA12 fly model
Yang et al., Int Immunopharmacol 2013
(Disease Models, Animal...) :
XN significantly decreased malondialdehyde, potentiated
superoxide dismutase and glutathione peroxidase, reduced Bax expression, promoted Bcl-xL and
inhibited caspase 3 activity in liver tissues compared with the animals without XN intervention