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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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ILK — PTEN

Text-mined interactions from Literome

Persad et al., Proc Natl Acad Sci U S A 2000 (Prostatic Neoplasms) : We now demonstrate that the activity of ILK is constitutively elevated in a serum- and anchorage independent manner in PTEN-mutant cells, and transfection of wild-type ( WT ) PTEN into these cells inhibits ILK activity
Mhashilkar et al., Mol Ther 2003 (Breast Neoplasms...) : Expression of the PI3K pathway members ( p85 PI3K, FAK, ILK-1 , Akt, and PLC-gamma ) was downregulated and expression of the PI3K antagonist PTEN was increased
Obara et al., Cancer Lett 2004 (Brain Neoplasms...) : Our results suggest that ILK is critical for the PTEN-sensitive regulation of PKB/Akt dependent cell survival
Edwards et al., Oncogene 2005 (Brain Neoplasms...) : The activity of ILK is constitutively elevated in a serum independent manner in PTEN mutant cells, and transfection of wild-type PTEN under the control of an inducible promoter into mutant PTEN cells inhibits ILK activity
Kuo et al., Virus Res 2013 : Immunofluorescence staining analysis showed that HBx disrupted stress fiber formation and that focal adhesion kinase ( FAK ) and integrin linked kinase (ILK) were regulated by HBx mediated phosphatase and tensin homolog (PTEN)