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TBCC — TGFB1
Text-mined interactions from Literome
Barcellini et al., Haematologica 2004
(Hemoglobinuria, Paroxysmal) :
In patients cytokines modulated normal and mutated clones differently :
TGF-b reduced the number of PIG-A- and PIG-A+
colony-forming-cells (CFC) , whereas TNF-alpha and IFN-gamma reduced PIG-A+ CFC only
Yao et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2007
:
The results showed that antagonizing
TGF-beta(1) in the course of EB growth could significantly
reduce the number of
BL-CFC ( P < 0.01 ), and the frequency of Flk-1 ( + ) cells was also decreased consistently
Keller et al., J Cell Biochem 1989
(Leukemia, Myeloid) :
In particular, CFU-GM, CFU-GEMM, BFU-E, and
HPP-CFC , the most immature colonies, were
inhibited by
TGF-beta 1 , whereas the more differentiated unipotent CFU-G, CFU-M, and CFU-E were not affected
Garbe et al., Br J Haematol 1997
(Lymphatic Diseases...) :
The inhibitory
effect of
TGF-beta 1 on
GM-CFC generation was reversed when it was washed out on day 6 of ex vivo expansion cultures, and total numbers of GM-CFC generated from expansion cultures then reached levels of untreated controls by day 16