Sanjabi et al., Proc Natl Acad Sci U S A 2000
:
These results reveal that a c-Rel containing complex is an essential and selective activator of p40 transcription, which may reflect unique regulatory mechanisms or biological functions of IL-12
Sun et al., Mol Immunol 2004
:
Furthermore, p300 was able to reinforce the c-Rel mediated activation of IL-12 p40 Tomczak et al., J Immunol 2006
(MAP Kinase Signaling System) :
Inhibition of the induction of IL-12 p40 by ERK was independent of c-Rel , a known positive regulator of IL-12 p40
Rottjakob et al., J Virol 1996
:
These results are not consistent with the hypothesis that p40 regulates cellular localization of v-Rel and c-Rel by the same mechanism ... Rather, these results support the hypothesis that p40 regulates cellular localization of v-Rel and c-Rel by distinct mechanisms