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CCK — STAT3

Text-mined interactions from Literome

Heldsinger et al., J Biol Chem 2011 (Ion Channel Gating) : Synergistic interaction between leptin and cholecystokinin in the rat nodose ganglia is mediated by PI3K and STAT3 signaling pathways : implications for leptin as a regulator of short term satiety ... Leptin/CCK-8 synergistically stimulated a 7.7-fold increase in phosphorylated STAT3 ( pSTAT3 ), which was inhibited by AG490, C3 transferase, PP2, LY294002, and wortmannin, but not PD98059
Gurda et al., Physiol Genomics 2012 : Moreover, immunohistochemistry showed a CCK dependent and acinar cell-specific increase in nuclear localization of p-STAT3 , with > 75 % nuclear occupancy in PI-fed mice vs. < 0.1 % in controls