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CXCL12 — NUP43

Text-mined interactions from Literome

Chernock et al., Blood 2001 : We and others have shown that the binding of SDF-1alpha to CXCR4 activates phosphatidylinositol-3 kinase ( PI-3 kinase ), p44/42 mitogen associated protein kinase, and the transcription factor nuclear factor-kappaB, and it also enhances the tyrosine phosphorylation and association of proteins involved in the formation of focal adhesions
Robledo et al., J Biol Chem 2001 (Melanoma...) : Additionally, Mig and SDF-1alpha activated MAPKs p44/42 and p38 on melanoma cells
Hideshima et al., Mol Cancer Ther 2002 (Multiple Myeloma) : In MM cell lines and patient MM cells, SDF-1alpha induces phosphorylation of p42/44 mitogen activated protein kinase, as well as Akt and its downstream target Bad, and also activates nuclear factor-kappaB
Ghosh et al., Mol Immunol 2006 : Further investigation of signaling studies to delineate the mechanism of inhibition revealed that cannabinoids enhance CXCL12 induced p44/42 MAP kinase activity
Korniejewska et al., Immunology 2011 : We report that CXCL4 induces intracellular calcium mobilization as well as Akt and p44/p42 extracellular signal regulated kinase phosphorylation, in activated human T lymphocytes