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CASP4 — CASP9

Text-mined interactions from Literome

Robertson et al., Crit Rev Toxicol 2000 : Caspase-9 can signal downstream and activate pro-caspase-3 and -7
Viswanath et al., J Neurosci 2001 (Disease Models, Animal...) : Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced Parkinson 's disease ... Caspase-9 inhibition prevented the activation of both caspase-3 and caspase-8 and also inhibited Bid cleavage, but not cytochrome c release
Robertson et al., Toxicology 2002 (Necrosis) : Caspase-9 can signal downstream and activate pro-caspase-3 and -7
Cuello et al., Cell Death Differ 2004 : Caspase-9 may further activate caspase-8 , generating an amplification loop
Martin et al., J Biol Chem 2005 : Caspase-9 cleaves and activates effector caspases, predominantly caspase-3 , resulting in the demise of the cell
Lang-Rollin et al., Apoptosis 2005 : Caspase 9 and 3 are processed, cytochrome c is released from the mitochondria and a dominant negative form of caspase 9 prevents death
Daher et al., Exp Dermatol 2006 : Caspase-9-DN and zLEHD-fmk both suppressed caspase-9 , -3, and -8 activity after UVB exposure, as well as proteolytic processing of procaspase-3 into its active form, DNA fragmentation factor 45 cleavage, and internucleosomal DNA fragmentation
Uchiyama et al., Infect Immun 2007 (Necrosis) : Caspase-9 activation was also detected in H37Rv infected cells, but H37Ra never induced such caspase-9 activation
Zhao et al., Tohoku J Exp Med 2008 (Myocardial Infarction...) : Caspase-9 cleaves and activates caspase-3
Tang et al., Oncol Rep 2009 (Adenocarcinoma...) : Caspase-9 and -3 inhibitors almost completely suppressed HCT induced caspase-9 and -3 activities
Shi et al., Toxicol Lett 2010 : Caspase 9 inhibition blocked the TNP induced activation of caspase 3 significantly
Ohsawa et al., Proc Natl Acad Sci U S A 2010 : Maturation of the olfactory sensory neurons by Apaf-1/caspase-9 mediated caspase activity ... Here, we provide unique evidence that Apaf-1/caspase-9 mediated caspase signaling regulates the development of olfactory sensory neurons ( OSNs ), which includes axonal projection, synapse formation, and maturation of these neurons
Liu et al., PloS one 2012 : Caspase-9 inhibitor could inhibit activation of pro-caspase-3 , and the inhibition of the function of Apaf-1 with FSBA blocked apoptosis, hinting that Apaf-1 could be involved in Sl-1 cell apoptosis induced by AfMNPV