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Apoptosis induction by Bcl-G ( S ) depended on the BH3 domain and was suppressed by coexpression of anti-apoptotic Bcl-X ( L ) protein
Ranuncolo et al., J Biol Chem 2008
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Although BCL6 can directly repress TP53 in centroblasts, BCL6 induced TP53 expression in primary fibroblasts and B-cells, and these cells underwent p53 dependent growth arrest and senescence in the presence of physiological levels of BCL6